Szigeti Andrea, Schneider Miklós, Ecsedy Mónika, Nagy Zoltán Zsolt, Récsán Zsuzsanna
Department of Ophthalmology, Semmelweis University, 39 Mária Str, 1085, Budapest, Hungary.
BMC Ophthalmol. 2015 Apr 30;15:45. doi: 10.1186/s12886-015-0031-1.
Results of ocular biometric measurements in retinal vein occlusion (RVO) eyes are still inconclusive and controversial. The aim of this study was to evaluate the association between ocular axial length (AL), vitreous chamber depth (VCD) and both central (CRVO) and branch retinal vein occlusions (BRVO) using optical low coherence reflectometry (OLCR).
Both eyes of 37 patients with unilateral CRVO (mean age: 66 ± 14 years, male:female - 21:16) and 46 patients with unilateral BRVO (mean age: 63 ± 12 years, male:female - 24:22) were enrolled in this study. The control group consisted of randomly selected single eyes of 67 age and gender matched volunteers without the presence or history of RVO (mean age: 64 ± 14 years, male:female - 34:33). Optical biometry was performed by OLCR biometer (LenStar LS 900). Average keratometry readings, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), AL and VCD of eyes with RVO were compared with those of fellow eyes using paired t-tests and with those of control eyes using independent t-tests.
Mean CCT, ACD and LT, average keratometry readings of affected RVO eyes, unaffected fellow eyes and control eyes was not statistically different in either groups. In eyes with CRVO mean AL and VCD of affected eyes were significantly shorter than those of control eyes (p < 0.001, p < 0.05), mean difference in AL and VCD between the affected and control eyes was 0.56 ± 0.15 mm and 0.45 ± 0.19 mm, respectively. In eyes with BRVO, mean AL of the affected eyes was significantly shorter with a mean difference of 0.57 ± 0.15 mm (p < 0.001) and the VCD was significantly shorter with a mean difference of 0.61 ± 0.15 mm (p < 0.001) comparing with the control eyes.
Shorter AL and VCD might be a potential anatomical predisposing factor for development either of CRVO or BRVO.
视网膜静脉阻塞（RVO）患者眼部生物测量结果仍无定论且存在争议。本研究旨在使用光学低相干反射ometry（OLCR）评估眼轴长度（AL）、玻璃体腔深度（VCD）与中央视网膜静脉阻塞（CRVO）和分支视网膜静脉阻塞（BRVO）之间的关联。
本研究纳入了37例单侧CRVO患者（平均年龄：66±14岁，男：女=21：16）和46例单侧BRVO患者（平均年龄：63±12岁，男：女=24：22）的双眼。对照组由67名年龄和性别匹配的志愿者的单眼组成，这些志愿者无RVO病史（平均年龄：64±14岁，男：女=34：33）。使用OLCR生物测量仪（LenStar LS 900）进行光学生物测量。使用配对t检验比较RVO患者患眼与对侧眼的平均角膜曲率读数、中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）、AL和VCD，并使用独立t检验与对照眼进行比较。
两组中，患RVO眼、未受影响的对侧眼和对照眼的平均CCT、ACD和LT、平均角膜曲率读数在统计学上均无差异。在CRVO患者中，患眼的平均AL和VCD显著短于对照眼（p<0.001，p<0.05），患眼与对照眼之间AL和VCD的平均差异分别为0.56±0.15mm和0.45±0.19mm。在BRVO患者中，患眼的平均AL显著短于对照眼，平均差异为0.57±0.15mm（p<0.001），VCD也显著短于对照眼（p<0.001），平均差异为0.61±0.15mm。
较短的AL和VCD可能是CRVO或BRVO发生的潜在解剖学易感因素。
