使用新型大相干长度扫频源光学相干断层扫描仪进行生物测量
Biometry measurements using a new large-coherence-length swept-source optical coherence tomographer.
作者信息
Shammas H John, Ortiz Sergio, Shammas Maya C, Kim Seong Hwan, Chong Changho
机构信息
From the Department of Ophthalmology (H.J. Shammas), The Keck School of Medicine of the University of Southern California Los Angeles, the Shammas Eye Medical Center (H.J. Shammas, M.C. Shammas), Lynwood, and Movu, Inc. (Ortiz, Kim, Chong), San Jose, California, USA.
From the Department of Ophthalmology (H.J. Shammas), The Keck School of Medicine of the University of Southern California Los Angeles, the Shammas Eye Medical Center (H.J. Shammas, M.C. Shammas), Lynwood, and Movu, Inc. (Ortiz, Kim, Chong), San Jose, California, USA.
出版信息
J Cataract Refract Surg. 2016 Jan;42(1):50-61. doi: 10.1016/j.jcrs.2015.07.042.
PURPOSE
To evaluate the repeatability and reproducibility of the measurements obtained with the Argos, a new biometer with swept-source optical coherence tomography (SS-OCT), and to compare them with the results obtained with the IOLMaster 500 (partial-coherence interferometry [PCI]) and the Lenstar LS 900 (optical low-coherence reflectometry [OLCR]) biometers.
SETTING
Private practice, Lynwood, California, USA.
DESIGN
Prospective observational study.
METHODS
All measurements were performed with the SS-OCT tomographer, the PCI biometer, and the OLCR biometer.
RESULTS
Eyes (n = 107) were measured to evaluate the axial length (AL), central corneal thickness (CCT), aqueous depth, anterior chamber depth (ACD), lens thickness, pupil size, corneal diameter, and anterior corneal radius of curvature (RAV). Repeatability and reproducibility of the SS-OCT measurements showed comparable values and a low variation rate, with an interset mean difference of 0.01 mm for AL, 0.01 mm for CCT, 0.01 mm for aqueous depth and ACD, 0.03 mm for lens thickness, 0.10 mm for pupil size, 0.14 mm for corneal diameter, and 0.02 mm for RAV. The SS-OCT device correctly measured the AL in 96% of the cases compared with 79% for the OLCR device and 77% for the PCI device. Comparisons between the PCI device and SS-OCT device were -0.01 ± 0.05 mm for AL, -0.17 ± 0.20 mm for ACD, and -0.01 ± 0.05 mm for RAV. Comparison between the OLCR device and the SS-OCT device was 0.01 ± 0.06 mm for AL, 0.08 ± 0.15 mm for ACD, 0.00 ± 0.05 mm for RAV, 0.00 ± 0.01 mm for CCT, 0.07 ± 0.14 mm for aqueous depth, -0.23 ± 0.22 mm for lens thickness, -0.29 ± 0.53 mm for pupil size, and -0.34 ± 0.76 mm for corneal diameter.
CONCLUSION
Axial length measurements with the new SS-OCT biometer were comparable to the PCI and OLCR measurements with a higher AL acquisition rate.
FINANCIAL DISCLOSURE
Dr. Shammas is a consultant to Movu, Inc. Drs. Ortiz, Kim, and Chong have proprietary interest in the new technology.
目的
评估采用扫频源光学相干断层扫描（SS-OCT）技术的新型生物测量仪Argos所获得测量值的可重复性和再现性，并将其与IOLMaster 500（部分相干干涉测量法[PCI]）和Lenstar LS 900（光学低相干反射测量法[OLCR]）生物测量仪所获得的结果进行比较。
设置
美国加利福尼亚州林伍德的私人诊所。
设计
前瞻性观察性研究。
方法
所有测量均使用SS-OCT断层扫描仪、PCI生物测量仪和OLCR生物测量仪进行。
结果
对107只眼睛进行测量，以评估眼轴长度（AL）、中央角膜厚度（CCT）、房水深度、前房深度（ACD）、晶状体厚度、瞳孔大小、角膜直径和角膜前表面曲率半径（RAV）。SS-OCT测量的可重复性和再现性显示出相当的值和较低的变异性，AL的组内平均差异为0.01mm，CCT为0.01mm，房水深度和ACD为0.01mm，晶状体厚度为0.03mm，瞳孔大小为0.10mm，角膜直径为0.14mm，RAV为0.02mm。与OLCR设备的79%和PCI设备的77%相比，SS-OCT设备在96%的病例中正确测量了AL。PCI设备与SS-OCT设备之间AL的比较为-0.01±0.05mm，ACD为-0.17±0.20mm，RAV为-0.01±0.05mm。OLCR设备与SS-OCT设备之间AL的比较为0.01±0.06mm，ACD为0.08±0.15mm，RAV为0.00±0.05mm，CCT为0.00±0.01mm，房水深度为0.07±0.14mm，晶状体厚度为-0.23±0.22mm，瞳孔大小为-0.29±0.53mm，角膜直径为-0.34±0.76mm。
结论
新型SS-OCT生物测量仪测量的眼轴长度与PCI和OLCR测量结果相当，且AL采集率更高。
财务披露
Shammas博士是Movu公司的顾问。Ortiz博士、Kim博士和Chong博士对这项新技术拥有专利权益。
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