Howsmon Daniel, Bequette B Wayne
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
J Diabetes Sci Technol. 2015 Apr 30;9(5):1126-37. doi: 10.1177/1932296815583507.
Soon after the discovery that insulin regulates blood glucose by Banting and Best in 1922, the symptoms and risks associated with hypoglycemia became widely recognized. This article reviews devices to warn individuals of impending hypo- and hyperglycemia; biosignals used by these devices include electroencephalography, electrocardiography, skin galvanic resistance, diabetes alert dogs, and continuous glucose monitors (CGMs). While systems based on other technology are increasing in performance and decreasing in size, CGM technology remains the best method for both reactive and predictive alarming of hypo- or hyperglycemia.
1922年班廷和贝斯特发现胰岛素可调节血糖后不久,与低血糖相关的症状和风险就得到了广泛认识。本文综述了用于警告个体即将发生低血糖和高血糖的设备;这些设备所使用的生物信号包括脑电图、心电图、皮肤电阻、糖尿病警示犬和连续血糖监测仪(CGM)。虽然基于其他技术的系统在性能上不断提高且尺寸不断减小,但CGM技术仍然是对低血糖或高血糖进行反应性和预测性报警的最佳方法。