在住院治疗环境中，运动对戒除甲基苯丙胺依赖个体的抑郁和焦虑症状的影响。
The Impact of Exercise On Depression and Anxiety Symptoms Among Abstinent Methamphetamine-Dependent Individuals in A Residential Treatment Setting.
作者信息
Rawson Richard A, Chudzynski Joy, Gonzales Rachel, Mooney Larissa, Dickerson Daniel, Ang Alfonso, Dolezal Brett, Cooper Christopher B
机构信息
Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
出版信息
J Subst Abuse Treat. 2015 Oct;57:36-40. doi: 10.1016/j.jsat.2015.04.007. Epub 2015 Apr 15.
BACKGROUND
This paper reports data from a study designed to determine the impact of an 8-week exercise program on depression and anxiety symptoms among newly abstinent methamphetamine (MA)-dependent individuals in residential treatment.
METHODS
One hundred thirty-five MA-dependent individuals, newly enrolled in residential treatment, were randomly assigned to receive either a 3-times-per-week, 60-minute structured exercise program for 8 weeks (24 sessions) or an equivalent number of health education sessions. Using mixed-modeling repeated-measures regression, we examined changes in weekly total depression and anxiety scores as measured by the Beck Depression Inventory and Beck Anxiety Inventory over the 8-week study period.
RESULTS
Mean age of participants was 31.7 (SD = 6.9); 70.4% were male and 48% Latino. Analyses indicate a significant effect of exercise on reducing depression (β = -0.63, P = 0.001) and anxiety (β = -0.95, P=0.001) symptoms (total scores) over the 8-week period compared to a health education control group. A significant dose interaction effect between session attendance and exercise was found as well on reducing depression (β = -0.61, P < 0.001) and anxiety symptoms (β = -0.22, P=0.009) over time compared to the control group.
CONCLUSIONS
Results support the role of a structured exercise program as an effective intervention for improving symptoms of depression and anxiety associated with MA abstinence.
背景
本文报告了一项研究的数据，该研究旨在确定为期8周的锻炼计划对住院治疗中刚戒除甲基苯丙胺（MA）依赖的个体的抑郁和焦虑症状的影响。
方法
135名新入院接受住院治疗的MA依赖个体被随机分配，一组接受每周3次、每次60分钟的结构化锻炼计划，为期8周（共24节课程），另一组接受等量的健康教育课程。我们使用混合模型重复测量回归分析，在为期8周的研究期间，通过贝克抑郁量表和贝克焦虑量表来检测每周抑郁和焦虑总分的变化。
结果
参与者的平均年龄为31.7岁（标准差=6.9）；70.4%为男性，48%为拉丁裔。分析表明，与健康教育对照组相比，在8周期间，锻炼对减轻抑郁（β=-0.63，P=0.001）和焦虑（β=-0.95，P=0.001）症状（总分）有显著效果。与对照组相比，还发现课程参与度和锻炼之间存在显著的剂量交互作用，随着时间推移，对减轻抑郁（β=-0.61，P<0.001）和焦虑症状（β=-0.22，P=0.009）有显著作用。
结论
结果支持结构化锻炼计划作为改善与MA戒除相关的抑郁和焦虑症状的有效干预措施的作用。
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