Cobos Raquel, Aizpuru Felipe, Parraza Naiara, Anitua Eduardo, Orive Gorka
Health Research Unit of Álava, Basque Health Service, Vitoria, Spain.
Curr Pharm Biotechnol. 2015;16(7):630-4. doi: 10.2174/138920101607150427111926.
"There is a growing body of evidence suggesting that wound healing in chronic diabetic foot ulcers is growth factor dependent, and that the therapeutic delivery of these growth factors to wounds topically, has the potential ability to accelerate wound healing in conjunction with conventional wound care". There is, however, confusion about the utility of platelet rich plasma because the studies that have evaluated them use a wide range of products (different platelet and leukocyte concentrations, different techniques and frequencies of application, very heterogeneous simple, and different endpoints) making almost impossible to compare data and draw conclusions. In this study, we have analyzed the different platelet rich plasma products from a new perspective: cost-efficiency. According to our data, we observe that platelet rich plasma is a cost-effective option that allows faster healing of ulcers, and that should be taken into account in patients with long evolution ulcers.
越来越多的证据表明,慢性糖尿病足溃疡的伤口愈合依赖生长因子,并且将这些生长因子局部递送至伤口进行治疗,有可能结合传统伤口护理加速伤口愈合。然而,关于富血小板血浆的效用存在困惑,因为评估它们的研究使用了广泛的产品(不同的血小板和白细胞浓度、不同的应用技术和频率、非常异质的制剂以及不同的终点),这使得几乎无法比较数据并得出结论。在本研究中,我们从一个新的角度分析了不同的富血小板血浆产品:成本效益。根据我们的数据,我们观察到富血小板血浆是一种具有成本效益的选择,可使溃疡更快愈合,对于患有长期溃疡的患者应予以考虑。