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富血小板血浆综述:历史、生物学、作用机制及分类

A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification.

作者信息

Alves Rubina, Grimalt Ramon

机构信息

Department of Dermatology, Universitat International Catalunya, Barcelona, Spain.

出版信息

Skin Appendage Disord. 2018 Jan;4(1):18-24. doi: 10.1159/000477353. Epub 2017 Jul 6.

Abstract

Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia. PRP is a biological product defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. It is obtained from the blood of patients collected before centrifugation. The knowledge of the biology, mechanism of action, and classification of the PRP should help clinicians better understand this new therapy and to easily sort and interpret the data available in the literature regarding PRP. In this review, we try to provide useful information for a better understanding of what should and should not be treated with PRP.

摘要

富血小板血浆(PRP)目前应用于不同的医学领域。最近,人们对PRP在皮肤科应用的兴趣有所增加。它被用于多种不同的应用中,如组织再生、伤口愈合、瘢痕修复、皮肤焕肤效果和脱发治疗。PRP是一种生物制品,定义为自体血液中血小板浓度高于基线的血浆部分。它是从患者离心前采集的血液中获得的。了解PRP的生物学、作用机制和分类,应有助于临床医生更好地理解这种新疗法,并轻松整理和解读文献中有关PRP的现有数据。在本综述中,我们试图提供有用的信息,以便更好地理解哪些情况应该用PRP治疗,哪些情况不应该用PRP治疗。

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