Wu Zhenkai, Zhao Dahang, Zhao Li, Liu Jianlin, Li Hai, Zhu Jie, Ma Fengcang, Porter Daniel Edward
Department of Pediatric Orthopaedics, Xin-Hua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China.
School of Materials Science & Engineering, University of Shanghai for Science and Technology, No. 516, Jungong Road, Shanghai, Shanghai, 200093, China.
J Orthop Surg Res. 2015 May 3;10:57. doi: 10.1186/s13018-015-0198-4.
The purpose of the animal study is to introduce a newly designed hinged plate and screw system for correction of angular deformities of the lower limbs. The technique was compared with the use of a conventional tension-band plate and screw system.
This is a randomized controlled animal trial. Eight 3-month-old Bama miniature pigs were used to establish animal models. In each animal, one leg was randomly allocated into study group and another leg into control group. Legs of the study group were corrected with a hinged plate and screw system, and legs of the control group were corrected with a conventional tension-band plate and screw system. The corrective rates of medial slope angle, medial proximal tibial angle, and angle of the two arms of the hinged plate were measured. Residual stress on the implants was also evaluated. A P < 0.05 was statistical significant.
At the final measurements of 18 weeks, the mean corrective rates of medial slope angle, medial proximal tibial angle, and angle of the two arms of the study group were 0.71°/week, 0.85°/week, and 2.18°/week, respectively; the data in the control group were 0.84°/week, 0.89°/week, and 2.13°/week, respectively. No significant difference was found between the groups regarding the mean corrective rates of the angles (P < 0.05). The mean residual stress in the study group was 643.35 MPa, and measurement in the control group was 1,273.63 MPa, with a significant difference (P < 0.05).
Compared to the conventional tension-band plate and screw system, the hinged plate and screw system may be more reliable for correction of angular deformities of the lower limb.
本动物研究的目的是引入一种新设计的用于矫正下肢角形畸形的铰链钢板及螺钉系统。该技术与传统张力带钢板及螺钉系统的使用进行了比较。
这是一项随机对照动物试验。使用8只3月龄巴马小型猪建立动物模型。在每只动物中，一条腿随机分配到研究组，另一条腿分配到对照组。研究组的腿用铰链钢板及螺钉系统进行矫正，对照组的腿用传统张力带钢板及螺钉系统进行矫正。测量内侧倾斜角、胫骨近端内侧角及铰链钢板两臂夹角的矫正率。还评估了植入物上的残余应力。P < 0.05具有统计学意义。
在18周的最终测量中，研究组内侧倾斜角、胫骨近端内侧角及铰链钢板两臂夹角的平均矫正率分别为0.71°/周、0.85°/周和2.18°/周；对照组的数据分别为0.84°/周、0.89°/周和2.13°/周。两组之间角度的平均矫正率无显著差异（P < 0.05）。研究组的平均残余应力为643.35MPa，对照组的测量值为1273.63MPa，差异有统计学意义（P < 0.05）。
与传统张力带钢板及螺钉系统相比，铰链钢板及螺钉系统在矫正下肢角形畸形方面可能更可靠。
