Zhang Hao, Huang Jing, Li Tianqi, Svanberg Sune, Svanberg Katarina
South China Normal University, University City Campus, Center for Optical and Electromagnetic Research, Research Building 5, 510006 Guangzhou, China.
South China Normal University, University City Campus, Center for Optical and Electromagnetic Research, Research Building 5, 510006 Guangzhou, ChinabLund University, Lund Laser Center, P.O. Box 118, SE-221 00 Lund, Sweden.
J Biomed Opt. 2015 May;20(5):57001. doi: 10.1117/1.JBO.20.5.057001.
A noninvasive optical technique, which is based on a combination of reflectance spectroscopy and gas in scattering media absorption spectroscopy, is demonstrated. It has the potential to improve diagnostics of middle ear infections. An ear phantom prepared with a tissue cavity, which was covered with scattering material, was used for spectroscopic measurements. Diffuse reflectance spectra of the phantom eardrum were measured with a reflectance probe. The presence of oxygen and water vapor as well as gas exchange in the phantom cavity were studied with a specially designed fiber-optic probe for backscattering detection geometry. The results suggest that this method can be developed for improved clinical detection of middle ear infection.
本文展示了一种基于反射光谱与散射介质中气体吸收光谱相结合的非侵入性光学技术。该技术具有改善中耳感染诊断的潜力。使用一个带有组织腔并覆盖有散射材料的耳模型进行光谱测量。用反射探头测量模型鼓膜的漫反射光谱。使用专门设计的用于背散射检测几何结构的光纤探头研究模型腔内氧气、水蒸气的存在以及气体交换情况。结果表明，该方法可进一步开发用于改善中耳感染的临床检测。
