INFANT Research Centre, University College Cork, Cork, Ireland.
Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland.
Pediatr Res. 2022 Nov;92(5):1240-1246. doi: 10.1038/s41390-022-02110-y. Epub 2022 May 23.
Gas in scattering media absorption spectroscopy (GASMAS) is a novel optical technology employing near-infrared light. It has a potential use in the medical setting as a monitoring and diagnostic tool by detecting molecular oxygen within gas pockets and thus may be a useful adjunct in respiratory monitoring. GASMAS has potential advantages over other monitoring devices currently used in clinical practice. It is a non-invasive, continuous, non-ionising technology and provides unique information about molecular oxygen content inside the lungs. GASMAS may have a future role in optimising respiratory management of neonates in different clinical scenarios such as monitoring cardiorespiratory transition in the delivery room, assessing surfactant deficiency, and optimising endotracheal tube positioning. This article aims to summarise current evidence exploring GASMAS application in a neonate, discuss possible clinical benefits, and compare with other devices that are currently used in neonatal care. IMPACT: This article presents a novel optical technique to measure lung oxygen concentrations that may have important clinical uses. This review summarises the current literature investigating the concept of optical lung oxygen measurement. Information from this review can guide researchers in future studies.
弥散介质中气体吸收光谱（GASMAS）是一种采用近红外光的新型光学技术。它在医疗环境中有作为监测和诊断工具的潜力，通过检测气腔内的分子氧，因此可能是呼吸监测的有用辅助手段。GASMAS 具有优于目前临床实践中使用的其他监测设备的潜在优势。它是非侵入性的、连续的、非电离的技术，并提供有关肺部内分子氧含量的独特信息。GASMAS 可能在优化不同临床情况下新生儿的呼吸管理方面发挥作用，例如在产房监测心肺过渡、评估表面活性剂缺乏以及优化气管内管定位。本文旨在总结目前探索 GASMAS 在新生儿中应用的证据，讨论可能的临床益处，并与目前在新生儿护理中使用的其他设备进行比较。
本文提出了一种测量肺氧浓度的新型光学技术，可能具有重要的临床用途。本文综述了目前研究光学肺氧测量概念的文献。本文综述提供的信息可以指导研究人员进行未来的研究。
