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新生儿普遍超声筛查中早期发育性髋关节发育不良的低发病率:危险因素分析与评估

Low incidence of early developmental dysplasia of the hip in universal ultrasonographic screening of newborns: analysis and evaluation of risk factors.

作者信息

Kolb Alexander, Schweiger Nina, Mailath-Pokorny Mariella, Kaider Alexandra, Hobusch Gerhard, Chiari Catharina, Windhager Reinhard

机构信息

Department of Orthopaedics and Orthopaedic Surgery, Medical University of Vienna, Waehringer Gürtel 18-20, 1090, Vienna, Austria.

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, 1090, Vienna, Austria.

出版信息

Int Orthop. 2016 Jan;40(1):123-7. doi: 10.1007/s00264-015-2799-2. Epub 2015 May 5.

Abstract

PURPOSE

Different timing and approaches to screening for developmental dysplasia of the hip (DDH) are used in the orthopaedic community. Thus ultrasonographic screening programs and reports based on clinical examinations produced differing incidence rates of DDH. Furthermore different risk factors and a change of incidence of DDH in the last decades were discussed. The purpose of this study was the evaluation of incidence and risk factors of the very early DDH in a modern cohort based on a universal ultrasound screening program.

METHODS

We analysed the results of the screening program performed at our institution: 5,356 consecutive hips of newborns were screened ultrasonographically and clinically according to the system published by R. Graf within the first two postnatal weeks [1]. A set of risk factors was analysed by univariate and multiple linear regression models.

RESULTS

Sonographic signs of developmental dysplasia of the hip were found in 0.24 % of the newborns. A significant negative influence of the risk factors birth weight, family history of DDH and female gender on the α-angle was found. Early or pre-term delivery showed a protective potential for DDH.

CONCLUSIONS

Our data show a very low incidence of DDH in the first two postnatal weeks. Despite the significance of the risk factors analysed, it has to be considered that these factors only showed low impact on the risk of early DDH. In conclusion we favour universal ultrasound screening for DDH at the age of six to eight weeks.

摘要

目的

骨科领域对于发育性髋关节发育不良(DDH)的筛查采用了不同的时机和方法。因此,超声筛查项目和基于临床检查的报告得出的DDH发病率有所不同。此外,还讨论了不同的风险因素以及过去几十年中DDH发病率的变化。本研究的目的是基于一项通用的超声筛查项目,评估现代队列中极早期DDH的发病率和风险因素。

方法

我们分析了在本机构进行的筛查项目结果:根据R. Graf发布的系统,在出生后的前两周内,对5356例连续新生儿的髋关节进行了超声和临床检查[1]。通过单变量和多元线性回归模型分析了一组风险因素。

结果

在0.24%的新生儿中发现了髋关节发育不良的超声征象。发现出生体重、DDH家族史和女性性别等风险因素对α角有显著的负面影响。早产或早期分娩对DDH有保护作用。

结论

我们的数据显示出生后前两周DDH的发病率非常低。尽管所分析的风险因素具有显著性,但必须考虑到这些因素对早期DDH风险的影响较小。总之,我们赞成在6至8周龄时对DDH进行通用超声筛查。

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