Ng Terry L, Hutton Brian, Clemons Mark
Division of Medical Oncology, Department of Medicine, and Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada; Ottawa Hospital Research Institute, Ottawa, Canada
Division of Medical Oncology, Department of Medicine, and Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada; Ottawa Hospital Research Institute, Ottawa, Canada.
Oncologist. 2015 Jun;20(6):576-83. doi: 10.1634/theoncologist.2014-0438. Epub 2015 May 6.
Despite advances in antiemetic therapy, chemotherapy-induced nausea and vomiting (CINV) remains the most feared and expected side effect of chemotherapy. Optimization of antiemetic therapy is important because CINV can lead to reduced quality of life, increased use of health care resources, and compromised treatment adherence. The evidence illustrates how antiemetic recommendations have evolved and raises ongoing issues and controversies in the management of CINV.
尽管在止吐治疗方面取得了进展,但化疗引起的恶心和呕吐(CINV)仍然是化疗最令人恐惧且预料之中的副作用。优化止吐治疗很重要,因为CINV会导致生活质量下降、医疗资源使用增加以及治疗依从性受损。证据表明了止吐建议是如何演变的,并提出了CINV管理中持续存在的问题和争议。