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围手术期洗必泰过敏:严重吗?

Perioperative chlorhexidine allergy: Is it serious?

作者信息

Abdallah Claude

机构信息

Division of Anesthesiology, The George Washington University Medical Center, Children's National Medical Center, Washington, D. C. 20010-2970, USA.

出版信息

J Anaesthesiol Clin Pharmacol. 2015 Apr-Jun;31(2):152-4. doi: 10.4103/0970-9185.155140.

DOI:10.4103/0970-9185.155140
PMID:25948892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4411825/
Abstract

Chlorhexidine is an antiseptic agent, commonly used, in many different preparations, and for multiple purposes. Despite its superior antimicrobial properties, chlorhexidine is a potentially allergenic substance. The following is a review of the current evidence-based knowledge of allergic reactions to chlorhexidine associated with surgical and interventional procedures.

摘要

氯己定是一种防腐剂,常用于多种不同制剂中,有多种用途。尽管氯己定具有卓越的抗菌特性,但它是一种潜在的过敏原。以下是对与手术和介入操作相关的氯己定过敏反应的当前循证知识的综述。

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本文引用的文献

1
Perioperative allergic reactions: experience in a Flemish referral centre.围手术期过敏反应:在一个佛兰芒转诊中心的经验
Allergol Immunopathol (Madr). 2014 Jul-Aug;42(4):348-54. doi: 10.1016/j.aller.2013.08.001. Epub 2013 Oct 23.
2
Chlorhexidine allergy due to topical application.
Indian J Dent Res. 2012 Sep-Oct;23(5):674-6. doi: 10.4103/0970-9290.107393.
3
Immediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.在英国,对氯己定的速发型超敏反应越来越受到关注。
Allergol Immunopathol (Madr). 2014 Jan-Feb;42(1):44-9. doi: 10.1016/j.aller.2012.08.001. Epub 2012 Dec 20.
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Anaphylactic reactions during anaesthesia and the perioperative period.麻醉及围手术期的过敏反应。
Anaesthesiol Intensive Ther. 2012 Aug 8;44(2):104-11.
5
The relevance of chlorhexidine contact allergy.氯己定接触过敏的相关性。
Contact Dermatitis. 2011 Apr;64(4):229-34. doi: 10.1111/j.1600-0536.2010.01851.x. Epub 2011 Jan 13.
6
Anaphylaxis to general anesthetics.对全身麻醉剂过敏
Chem Immunol Allergy. 2010;95:180-189. doi: 10.1159/000315951. Epub 2010 Jun 1.
7
IgE-mediated chlorhexidine allergy: a new occupational hazard?IgE 介导的洗必泰过敏:一种新的职业危害?
Occup Med (Lond). 2009 Jun;59(4):270-2. doi: 10.1093/occmed/kqp042. Epub 2009 Mar 26.
8
Review of procedures for investigation of anaesthesia-associated anaphylaxis in Newcastle, Australia.澳大利亚纽卡斯尔麻醉相关过敏反应调查程序综述。
Anaesth Intensive Care. 2008 Mar;36(2):201-7. doi: 10.1177/0310057X0803600210.
9
IgE-mediated allergy to chlorhexidine.对氯己定的IgE介导的过敏反应。
J Allergy Clin Immunol. 2007 Aug;120(2):409-15. doi: 10.1016/j.jaci.2007.04.029. Epub 2007 Jun 7.
10
Allergic reactions in anaesthesia: are suspected causes confirmed on subsequent testing?麻醉中的过敏反应:后续检测是否证实了疑似病因?
Br J Anaesth. 2005 Oct;95(4):468-71. doi: 10.1093/bja/aei198. Epub 2005 Aug 12.