Kalpana R, Thubashini M, Sundharam B Sivapatha
Department of Oral and Maxillofacial Pathology, Rathnavel Subramaniam Educational Trust RVS Dental College and Hospital, Kannampalayam, Sulur, Coimbatore, India.
Department of Oral and Maxillofacial Pathology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India.
J Oral Maxillofac Pathol. 2014 Sep-Dec;18(3):361-4. doi: 10.4103/0973-029X.151313.
The present study was undertaken to estimate and compare salivary interleukin-2 (IL-2) levels in patients with recurrent aphthous stomatitis, among healthy controls and their variation with age and sex.
Saliva was collected from 60 patients within the age range of 16-60 years which included 30 patients (17 Females and 13 Males) with recurrent aphthous stomatitis and healthy control group consisted of 30 participants (18 Females and 12 Males). IL-2 estimation was done in both the groups using enzyme linked immunosorbent assay (ELISA). Statistical analysis of the data was done using Independent 't' test.
The results showed increased salivary IL-2 levels in patients with recurrent aphthous stomatitis compared to the healthy controls. The IL-2 levels were also increased in patients with the age group of 16-30 years compared to other age groups. Similar increase of IL-2 was also seen in female patients.
Age related and sex related alterations of IL-2 in recurrent aphthous stomatitis patients were observed.
本研究旨在评估和比较复发性阿弗他口炎患者、健康对照者的唾液白细胞介素-2（IL-2）水平，以及其随年龄和性别的变化。
收集了60例年龄在16至60岁之间的患者的唾液，其中包括30例复发性阿弗他口炎患者（17名女性和13名男性），健康对照组由30名参与者组成（18名女性和12名男性）。两组均采用酶联免疫吸附测定（ELISA）法进行IL-2评估。使用独立样本t检验对数据进行统计分析。
结果显示，与健康对照组相比，复发性阿弗他口炎患者的唾液IL-2水平升高。与其他年龄组相比，16至30岁年龄组患者的IL-2水平也升高。女性患者中也观察到类似的IL-2升高情况。
观察到复发性阿弗他口炎患者中IL-2存在与年龄和性别相关的变化。
