Physical Sciences Division, Polymer Laboratory, Institute of Advanced Study in Science and Technology, Guwahati, Assam 781035, India.
ACS Appl Mater Interfaces. 2015 Jun 3;7(21):11195-202. doi: 10.1021/acsami.5b01102. Epub 2015 May 20.
Rapid detection of picric acid in real sample is of outmost importance from the perspective of health, safety, and environment. In this study, a very simple and cost-effective detection of picric acid is accomplished by developing a couple of biobased conjugates curcumin-cysteine (CC) and curcumin-tryptophan (CT), which undergo efficient fluorescence turn on toward picric acid in aqueous media. Both the probes experience about 26.5-fold fluorescence enhancements at 70 nM concentration of the analyte. Here, the fluorescence turn on process is governed by the aggregation induced emission, which is induced from the electrostatic interaction between the conjugates with picric acid. The detection limit of CC and CT are about 13.51 and 13.54 nM of picric acid, respectively. Importantly, both the probes exhibit high selectivity and low interference of other analogues toward the detection of picric acid. In addition, the probes are highly photostable, show low response time and are practically applicable for sensing picric acid in real environmental samples, which is the ultimate goal of this work.
从健康、安全和环境的角度来看，快速检测样品中的苦味酸至关重要。在这项研究中，通过开发几种生物基缀合物姜黄素-半胱氨酸（CC）和姜黄素-色氨酸（CT），实现了对苦味酸的非常简单且具有成本效益的检测，这两种缀合物在水介质中对苦味酸表现出高效的荧光开启。在分析物浓度为 70 nM 时，两种探针的荧光增强约 26.5 倍。在这里，荧光开启过程受聚集体诱导发射的控制，这是由共轭物与苦味酸之间的静电相互作用诱导的。CC 和 CT 的检测限分别约为 13.51 和 13.54 nM 的苦味酸。重要的是，两种探针对苦味酸的检测均表现出高选择性和低干扰其他类似物的特性。此外，这些探针具有高稳定性、低响应时间，可实际应用于检测实际环境样品中的苦味酸，这是这项工作的最终目标。
