Stoll Matthew L
University of Alabama at Birmingham, CPP N 210 M, 1600 7th Avenue South, Birmingham, AL 35233-1711, USA.
Clin Immunol. 2015 Aug;159(2):134-42. doi: 10.1016/j.clim.2015.05.001. Epub 2015 May 9.
The last decade has witnessed an explosion of studies evaluating the impact of the human microbiota on a variety of disease states. The microbiota can impact diseases in multiple ways, including through abnormalities in the diversity and contents of the microbiota, as well as by acting as targets of immunologic dysregulation. Herein, evidence that the microbiota in spondyloarthritis is both altered and abnormally targeted by the immune system will be presented.
在过去十年中，评估人类微生物群对多种疾病状态影响的研究呈爆发式增长。微生物群可通过多种方式影响疾病，包括微生物群多样性和组成的异常，以及作为免疫失调的靶点。本文将展示有关脊柱关节炎中微生物群发生改变且被免疫系统异常靶向的证据。
