De Rienzo B, Mongiardo N, Pellegrino F, Coppini M, Lami G, Zanchetta G, Borghi V, Cocchi I, Squadrini F, Giannetti A
Department of Infectious and Tropical Diseases, University of Modena, Italy.
Arch Dermatol Res. 1989;281(6):369-72. doi: 10.1007/BF00455318.
The transmission of the human immunodeficiency virus (HIV) was studied in 647 subjects who presented no apparent risk factors for the infection other than having had promiscuous heterosexual relations, heterosexual relations with people with an elevated risk of infection, or heterosexual relations with people infected by human immunodeficiency virus. Thirty subjects were found to be seropositive for anti-human immunodeficiency virus antibodies. The elevated risk factors included being the habitual partner of a person at risk of infection or of a person who was infected by human immunodeficiency virus, or being the partner of a patient with acquired immunodeficiency syndrome. The transmission of the virus was verified in 13 of 284 subjects (4.57%) who had had heterosexual intercourse three or more times with persons at risk and in 16 of 101 subjects (15.84%) who had had heterosexual intercourse three or more times with persons who were seropositive for human immunodeficiency virus antibodies. No significant correlation between human immunodeficiency virus infection and a history of sexually transmitted infections, nor between human immunodeficiency virus infection and female subjects was found. These data suggest that the epidemic of acquired immunodeficiency syndrome can also spread through heterosexual relations, even if the possibility of becoming infected in this way seems at the moment limited to particular risk behaviors.
对647名受试者的人类免疫缺陷病毒（HIV）传播情况进行了研究，这些受试者除了有过滥交异性性行为、与感染风险较高的人发生异性性行为或与感染人类免疫缺陷病毒的人发生异性性行为外，没有其他明显的感染风险因素。发现30名受试者抗人类免疫缺陷病毒抗体呈血清阳性。感染风险较高的因素包括成为感染风险较高的人或感染人类免疫缺陷病毒的人的固定伴侣，或成为获得性免疫缺陷综合征患者的伴侣。在284名与感染风险较高的人发生过三次或更多次异性性行为的受试者中，有13人（4.57%）证实病毒传播；在101名与抗人类免疫缺陷病毒抗体呈血清阳性的人发生过三次或更多次异性性行为的受试者中，有16人（15.84%）证实病毒传播。未发现人类免疫缺陷病毒感染与性传播感染病史之间、以及人类免疫缺陷病毒感染与女性受试者之间存在显著相关性。这些数据表明，获得性免疫缺陷综合征的流行也可通过异性性行为传播，即使目前通过这种方式感染的可能性似乎仅限于特定的危险行为。
