Dommergues J P, Archambeaud M P, Ducot B, Gerval Y, Hiard C, Rossignol C, Tchernia G
Département de Pédiatrie, Hôpital de Bicêtre, Le Kremlin-Bicêtre.
Arch Fr Pediatr. 1989 Aug-Sep;46(7):487-90.
A longitudinal study of iron deficiency and of psychomotor development was carried out in 147 children followed between the ages of 10 months and 4 years in 2 well-baby out-patient clinics in Paris area. The tests used were those of Brunet-Lézine. The frequency of iron deficiency anemia was 22% at age 10 months, 9% at 2 years and 2% at 4 years. Ferritin blood levels were abnormally low in 35% of patients at 10 months of age, in 36% at 2 years and in 40% at 4 years. No significant correlation could be found between the Development Quotient (DQ) and biological data at the ages of 10 months and 4 years. On the other hand, at age 2, the mean DQ values were higher in children without deficiency than in those with deficiency with respect to the following biological parameters: hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration. These differences persisted even after taking into account variables known to influence psychomotor development.
在巴黎地区的两家婴儿门诊诊所，对147名年龄在10个月至4岁之间的儿童进行了一项关于缺铁与精神运动发育的纵向研究。所使用的测试是布鲁内 - 勒齐纳测试。缺铁性贫血的发生率在10个月大时为22%，2岁时为9%，4岁时为2%。10个月大的患者中35%的铁蛋白血水平异常低，2岁时为36%，4岁时为40%。在10个月和4岁时，发育商（DQ）与生物学数据之间未发现显著相关性。另一方面，在2岁时，就以下生物学参数而言，无缺铁的儿童的平均DQ值高于缺铁儿童：血红蛋白、平均红细胞体积、平均红细胞血红蛋白浓度。即使考虑到已知会影响精神运动发育的变量，这些差异仍然存在。
