Varvaresou A, Iakovou K
Laboratory of Cosmetology, Department of Aesthetics and Cosmetology, Technological Educational Institution of Athens, Athens, Greece.
Department of Drugs, Ministry of Health, Athens, Greece.
Lett Appl Microbiol. 2015 Sep;61(3):214-23. doi: 10.1111/lam.12440. Epub 2015 Jun 25.
Biosurfactants are surface-active biomolecules that are produced by various micro-organisms. They show unique properties i.e. lower toxicity, higher biodegradability and environmental compatibility compared to their chemical counterparts. Glycolipids and lipopeptides have prompted application in biotechnology and cosmetics due to their multi-functional profile i.e. detergency, emulsifying, foaming and skin hydrating properties. Additionally, some of them can be served as antimicrobials. In this study the current status of research and development on rhamnolipids, sophorolipids, mannosyloerythritol lipids, trehalipids, xylolipids and lipopeptides particularly their commercial application in cosmetics and biopharmaceuticals, is described.
生物表面活性剂是由多种微生物产生的具有表面活性的生物分子。与化学合成的表面活性剂相比,它们具有独特的性质,即更低的毒性、更高的生物降解性和环境兼容性。糖脂和脂肽因其具有多功能特性,如去污、乳化、发泡和皮肤保湿性能,已在生物技术和化妆品领域得到广泛应用。此外,其中一些还可作为抗菌剂。本研究描述了鼠李糖脂、槐糖脂、甘露糖赤藓糖醇脂、海藻糖脂、木糖脂和脂肽的研发现状,特别是它们在化妆品和生物制药中的商业应用。