腿部抽筋。
Leg cramps.
作者信息
Young Gavin
机构信息
Temple Sowerby Medical Practice, Penrith, UK.
出版信息
BMJ Clin Evid. 2015 May 13;2015:1113.
INTRODUCTION
Involuntary, localised leg cramps are common and typically affect the calf muscles at night.
METHODS AND OUTCOMES
We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments for idiopathic leg cramps? What are the effects of treatments for leg cramps in pregnancy? We searched: Medline, Embase, The Cochrane Library, and other important databases up to January 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS
We found 16 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS
In this systematic review we present information relating to the effectiveness and safety of the following interventions: analgesics; anti-epileptic drugs; calcium salts; diltiazem; magnesium salts; multivitamin and mineral supplements; quinine; sodium chloride; stretching exercises; verapamil; vitamin B6 (pyridoxine); and vitamin E.
引言
非自愿性局部腿部痉挛很常见，通常在夜间影响小腿肌肉。
方法与结果
我们进行了一项系统评价，旨在回答以下临床问题：特发性腿部痉挛的治疗效果如何？孕期腿部痉挛的治疗效果如何？我们检索了：截至2014年1月的医学文献数据库（Medline）、荷兰医学文摘数据库（Embase）、考克兰图书馆及其他重要数据库（临床证据综述会定期更新；请查看我们的网站获取本综述的最新版本）。我们纳入了来自美国食品药品监督管理局（FDA）和英国药品和医疗产品监管局（MHRA）等相关组织的危害警示。
结果
我们发现16项研究符合我们的纳入标准。我们对干预措施的证据质量进行了GRADE评估。
结论
在本系统评价中，我们呈现了以下干预措施有效性和安全性的相关信息：镇痛药；抗癫痫药；钙盐；地尔硫䓬；镁盐；多种维生素和矿物质补充剂；奎宁；氯化钠；伸展运动；维拉帕米；维生素B6（吡哆醇）；以及维生素E。
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