Zhu Jie-Gao, Zhang Zhong-Tao, Wu Guo-Cong, Han Wei, Wang Kang-Li
Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China ; Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing, 100050 People's Republic of China.
Indian J Surg. 2015 Apr;77(Suppl 1):185-7. doi: 10.1007/s12262-015-1256-1. Epub 2015 Mar 11.
Collision tumors are thought to arise from the accidental meeting of two independent tumors. Adenocarcinoma is the most common malignant rectal tumor, while neuroendocrine tumor (NET) is relatively rare. Due to the endoscopy and reporting, the overall incidence of NETs was increasing recently but still less than 1 per 100,000. This means that a combination of an adenocarcinoma and NET is a very rare finding and an actual collision of these tumors even more so. We report here a highly unusual case of a 64-year-old woman who had collision tumors composed of a primary rectal adenocarcinoma and NET showing a "side by side" pattern. Resection margins are free of both the tumors. The postoperative course was uneventful. The patient underwent a protocol CT scan at 3 months after surgery, which did not show any recurrence. Both the malignant adenocarcinoma and the NET would make a great influence in the rest lifetime and a follow up will be continued, although the CT did not show any recurrence until now. To the best of our knowledge, this is the first reported case of such an occurrence.
碰撞瘤被认为是由两个独立肿瘤偶然相遇而产生的。腺癌是最常见的直肠恶性肿瘤，而神经内分泌肿瘤（NET）相对罕见。由于内镜检查和报告，近年来NET的总体发病率呈上升趋势，但仍低于十万分之一。这意味着腺癌和NET同时出现的情况非常罕见，而这两种肿瘤实际发生碰撞的情况更是如此。我们在此报告一例非常罕见的病例，一名64岁女性患有由原发性直肠腺癌和呈“并排”模式的NET组成的碰撞瘤。切除边缘均未发现肿瘤。术后过程顺利。患者术后3个月接受了方案规定的CT扫描，未显示任何复发迹象。尽管目前CT未显示任何复发，但恶性腺癌和NET都将对患者的余生产生重大影响，因此仍将继续进行随访。据我们所知，这是首例报道的此类病例。
