Lugito Nata Pratama Hardjo, Gunawan Edy, Chandra Margaret, Kurniawan Andree
Department of Internal Medicine, Pelita Harapan University, Banten, Indonesia.
Resident Medical Officer, Siloam Karawaci General Hospital, Tangerang, Indonesia.
J Clin Imaging Sci. 2015 Apr 30;5:21. doi: 10.4103/2156-7514.156123. eCollection 2015.
Acute pancreatitis is an inflammatory disease of the pancreas. The most common cause of acute pancreatitis is gallstone impacting the distal common bile-pancreatic duct (38%) and alcoholism (36%). There have been a few reports in the literature of acute pancreatitis associated with an obstructed urinary system. This case describes a 38-year-old male with acute pancreatitis occurring in the setting of hydronephrosis. A magnetic resonance cholangiopancreaticography (MRCP) showed right-sided severe hydronephrosis pushing the duodenum and head of pancreas anteriorly, thus obliterating distal segment of the common bile duct. There were also multiple right renal stones causing ureteral obstruction and hydronephrosis. Right nephrostomy was performed to release bile duct obstruction. However, sepsis and disseminated intravascular coagulation developed as a complication of acute pancreatitis, and the patient passed away. Although gallstone and alcoholism are the most common causes of acute pancreatitis, other causes should always be considered. Physicians should be aware of right hydronephrosis as one of the possible causes of acute pancreatitis in their workup of patients.
急性胰腺炎是胰腺的一种炎症性疾病。急性胰腺炎最常见的病因是胆结石阻塞胆总管远端-胰管(38%)和酗酒(36%)。文献中曾有少数关于急性胰腺炎与泌尿系统梗阻相关的报道。本病例描述了一名38岁男性,在肾积水的情况下发生急性胰腺炎。磁共振胰胆管造影(MRCP)显示右侧严重肾积水将十二指肠和胰头向前推移,从而使胆总管远端闭塞。此外,还有多个右肾结石导致输尿管梗阻和肾积水。行右肾造瘘术以解除胆管梗阻。然而,作为急性胰腺炎的并发症,患者发生了脓毒症和弥散性血管内凝血,最终死亡。尽管胆结石和酗酒是急性胰腺炎最常见的病因,但其他病因也应始终予以考虑。医生在对患者进行检查时应意识到右肾积水是急性胰腺炎的可能病因之一。