Lee Seung-Wook, Nam Min-Ho, Lee Byung-Cheol
Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Dongdaemun-Gu, Seoul 02447, Republic of Korea.
Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Dongdaemun-Gu, Seoul 02447, Republic of Korea.
Exp Ther Med. 2017 Jun;13(6):3249-3256. doi: 10.3892/etm.2017.4379. Epub 2017 Apr 25.
Herbal acupuncture (HA) is a modern adjunctive technique in which natural herbs or biologic substances are injected into acupuncture points. The objective of this systematic review was to evaluate evidence of the effectiveness of HA for type 2 diabetes mellitus (T2DM). Three databases were searched. The included randomized controlled trials (RCTs) evaluated HA in controls and patients with T2DM and reported at least one of the following: Fasting blood glucose (FBG), postprandial (PP2hr) glucose and glycated hemoglobin (HbA1c). In a meta-analysis of seven RCTs (n=598 patients), HA significantly reduced levels of FBG, PP2hr glucose and HbA1c (P<0.0001, P=0.0005 and P=0.004, respectively). There was no significant effect of HA on total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, or triglyceride level. High degrees of heterogeneity were present for all analyses except HDL-cholesterol and LDL-cholesterol. HA might have a beneficial effect on FBG, PP2hr glucose and HbA1c levels in patients with T2DM; however, because of several limitations, the results are inconclusive. Therefore, additional rigorous RCTs are warranted to overcome the limitations of previous studies.
草药针灸（HA）是一种现代辅助技术，即将天然草药或生物物质注入穴位。本系统评价的目的是评估草药针灸治疗2型糖尿病（T2DM）有效性的证据。检索了三个数据库。纳入的随机对照试验（RCT）对T2DM对照组和患者进行了草药针灸评估，并报告了以下至少一项指标：空腹血糖（FBG）、餐后2小时血糖（PP2hr）和糖化血红蛋白（HbA1c）。在对7项RCT（n = 598例患者）的荟萃分析中，草药针灸显著降低了FBG、PP2hr血糖和HbA1c水平（分别为P < 0.0001、P = 0.0005和P = 0.004）。草药针灸对总胆固醇、高密度脂蛋白（HDL）胆固醇、低密度脂蛋白（LDL）胆固醇或甘油三酯水平无显著影响。除HDL胆固醇和LDL胆固醇外，所有分析均存在高度异质性。草药针灸可能对T2DM患者的FBG、PP2hr血糖和HbA1c水平有有益影响；然而，由于存在一些局限性，结果尚无定论。因此，有必要进行更多严格的RCT以克服既往研究的局限性。
