RACK1，作为一个异三聚体 G 蛋白和一个 MAPK 级联反应的支架。
RACK1, scaffolding a heterotrimeric G protein and a MAPK cascade.
机构信息
State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China; Division of Biochemistry, Interdisciplinary Plant Group, and Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
出版信息
Trends Plant Sci. 2015 Jul;20(7):405-7. doi: 10.1016/j.tplants.2015.05.002. Epub 2015 May 16.
Scaffold proteins of mitogen-activated protein kinase (MAPK) cascades play crucial roles in determining signal specificity, amplitude, and duration in yeast and mammals. Recently, RACK1 was identified as the first plant MAPK scaffold protein that connects heterotrimeric G protein with a MAPK cascade to form a unique signaling pathway in plant immunity.
丝裂原活化蛋白激酶（MAPK）级联的支架蛋白在酵母和哺乳动物中对确定信号的特异性、幅度和持续时间起着至关重要的作用。最近，RACK1 被确定为第一个植物 MAPK 支架蛋白，它将异三聚体 G 蛋白与 MAPK 级联连接起来，在植物免疫中形成独特的信号通路。
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