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[衣原体诱导性关节炎的临床与血清学特征]

[Clinical and serological characterization of Chlamydia-induced arthritis].

作者信息

Wollenhaupt H J, Schneider C, Zeidler H, Krech T, Kuntz B M

机构信息

Abteilung Rheumatologie, Zentrum Innere Medizin und Dermatologie der Medizinischen Hochschule Hannover.

出版信息

Dtsch Med Wochenschr. 1989 Dec 1;114(50):1949-54. doi: 10.1055/s-2008-1066852.

DOI:10.1055/s-2008-1066852
PMID:2598790
Abstract

Chlamydia-induced arthritis was diagnosed in 32 patients (18 men and 14 women; mean age 33 [17-54] years). 13 were HLA-B27 positive. In 19 patients the arthritis was largely confined to one joint. Enthesopathies occurred in 14 patients, and in 13 sacroiliitis was diagnosed radiologically. The most frequent extra-articular changes affected the urogenital system (26 cases). The full Reiter syndrome was present in seven patients (four men, three women). All patients had serum antibodies against Chlamydia. In 16 patients Chlamydia was diagnosed as the causative organism by urogenital swab. Chlamydia-induced arthritis differs from other arthritides in the high proportion of HLA-B27 negative patients.

摘要

32例患者被诊断为衣原体感染所致关节炎(18例男性,14例女性;平均年龄33 [17 - 54]岁)。13例为HLA - B27阳性。19例患者的关节炎主要局限于一个关节。14例患者出现附着点病,13例经放射学诊断为骶髂关节炎。最常见的关节外改变累及泌尿生殖系统(26例)。7例患者出现完全型赖特综合征(4例男性,3例女性)。所有患者血清中均有抗衣原体抗体。16例患者经泌尿生殖道拭子检查诊断衣原体为病原体。衣原体感染所致关节炎与其他关节炎不同之处在于HLA - B27阴性患者比例较高。

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[Serum IgG antibodies to Chlamydia trachomatis in HLA-B-27 positive patients with rheumatic diseases].
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引用本文的文献

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Z Rheumatol. 2022 Oct;81(8):692-698. doi: 10.1007/s00393-022-01253-x. Epub 2022 Aug 25.
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Causality of Chlamydiae in Arthritis and Spondyloarthritis: a Plea for Increased Translational Research.衣原体在关节炎和脊柱关节炎中的因果关系:呼吁加强转化研究
Curr Rheumatol Rep. 2016 Feb;18(2):9. doi: 10.1007/s11926-015-0559-3.
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The value of specific antibody detection and culture in the diagnosis of reactive arthritis.特异性抗体检测及培养在反应性关节炎诊断中的价值
Clin Rheumatol. 1993 Jun;12(2):245-52. doi: 10.1007/BF02231536.
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Chlamydiae as pathogens--an overview of diagnostic techniques, clinical features, and therapy of human infections.衣原体作为病原体——人类感染的诊断技术、临床特征及治疗概述
Klin Wochenschr. 1991 Aug 1;69(11):463-73. doi: 10.1007/BF01649417.