Hu Jinglei, Wysocki Adam, Winkler Roland G, Gompper Gerhard
Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.
Sci Rep. 2015 May 20;5:9586. doi: 10.1038/srep09586.
Bacteria such as Escherichia coli swim along circular trajectories adjacent to surfaces. Thereby, the orientation (clockwise, counterclockwise) and the curvature depend on the surface properties. We employ mesoscale hydrodynamic simulations of a mechano-elastic model of E. coli, with a spherocylindrical body propelled by a bundle of rotating helical flagella, to study quantitatively the curvature of the appearing circular trajectories. We demonstrate that the cell is sensitive to nanoscale changes in the surface slip length. The results are employed to propose a novel approach to directing bacterial motion on striped surfaces with different slip lengths, which implies a transformation of the circular motion into a snaking motion along the stripe boundaries. The feasibility of this approach is demonstrated by a simulation of active Brownian rods, which also reveals a dependence of directional motion on the stripe width.
诸如大肠杆菌这样的细菌会沿着靠近表面的圆形轨迹游动。因此，其游动方向（顺时针、逆时针）和曲率取决于表面特性。我们采用大肠杆菌的机械弹性模型进行中尺度流体动力学模拟，该模型具有由一束旋转螺旋鞭毛驱动的球柱形身体，以定量研究出现的圆形轨迹的曲率。我们证明细胞对表面滑移长度的纳米级变化敏感。这些结果被用于提出一种在具有不同滑移长度的条纹表面上引导细菌运动的新方法，这意味着将圆周运动转变为沿条纹边界的蜿蜒运动。通过对活性布朗粒子的模拟证明了这种方法的可行性，该模拟还揭示了定向运动对条纹宽度的依赖性。
