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乌拉圭全国100%无烟法律对支气管痉挛急诊就诊的影响。

Effect of Uruguay's National 100% Smokefree Law on Emergency Visits for Bronchospasm.

作者信息

Kalkhoran Sara, Sebrié Ernesto M, Sandoya Edgardo, Glantz Stanton A

机构信息

Department of Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, California.

Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, New York.

出版信息

Am J Prev Med. 2015 Jul;49(1):85-8. doi: 10.1016/j.amepre.2014.12.009. Epub 2015 May 18.

Abstract

INTRODUCTION

Implementation of smokefree laws is followed by drops in hospital admissions for cardiovascular diseases and asthma. The impact of smokefree laws on use of non-hospital medical services has not been assessed. The purpose of this study is to evaluate the impact of Uruguay's national 100% smokefree legislation on non-hospital emergency care visits, hospitalizations for bronchospasm, and bronchodilator use.

METHODS

The monthly number of non-hospital emergency care visits and hospitalizations for bronchospasm, as well as monthly puffs of bronchodilators (total and per person), from 3 years prior to the adoption of the 100% smokefree policy on March 1, 2006, through 5 years after the policy were assessed using interrupted time series negative binomial regression. Data analysis was conducted in 2014.

RESULTS

The incidence of non-hospital emergency visits for bronchospasm decreased by 15% (incidence rate ratio [IRR]=0.85, 95% CI=0.76, 0.94) following implementation of the law. Hospitalizations for bronchospasm did not change significantly (IRR=0.89, 95% CI=0.66, 1.21). Total monthly puffs of salbutamol and ipratropium administered in the non-hospital emergency setting decreased by 224 (95% CI=-372, -76) and 179 (95% CI=-340, -18.6), respectively, from means of 1,222 and 1,007 before the law.

CONCLUSIONS

Uruguay's 100% smokefree law was followed by fewer emergency visits for bronchospasm and less need for treatment, supporting adoption of such policies in low- and middle-income countries to reduce the disease burden and healthcare costs associated with smoking.

摘要

引言

无烟法律实施后,心血管疾病和哮喘的住院人数有所下降。无烟法律对非医院医疗服务使用的影响尚未得到评估。本研究的目的是评估乌拉圭全国100%无烟立法对非医院急诊就诊、支气管痉挛住院治疗以及支气管扩张剂使用的影响。

方法

采用中断时间序列负二项回归分析,评估从2006年3月1日实施100%无烟政策前3年至政策实施后5年期间,每月非医院急诊就诊和支气管痉挛住院的次数,以及每月支气管扩张剂的使用量(总量和人均量)。数据分析于2014年进行。

结果

法律实施后,支气管痉挛的非医院急诊就诊发生率下降了15%(发生率比[IRR]=0.85,95%置信区间[CI]=0.76,0.94)。支气管痉挛的住院人数没有显著变化(IRR=0.89,95%CI=0.66,1.21)。在非医院急诊环境中,沙丁胺醇和异丙托溴铵的每月使用总量分别比法律实施前的均值1222和1007减少了224(95%CI=-372,-76)和179(95%CI=-340,-18.6)。

结论

乌拉圭的100%无烟法律实施后,支气管痉挛的急诊就诊次数减少,治疗需求降低,这支持在低收入和中等收入国家采用此类政策,以减轻与吸烟相关的疾病负担和医疗费用。

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