van Rijsbergen Mariëlle W A, Mark Ruth E, de Kort Paul L M, Sitskoorn Margriet M
Department of Cognitive Neuropsychology, CoRPS-Centre of Research on Psychology in Somatic Diseases, Tilburg University, Tilburg, The Netherlands.
Department of Cognitive Neuropsychology, CoRPS-Centre of Research on Psychology in Somatic Diseases, Tilburg University, Tilburg, The Netherlands.
J Stroke Cerebrovasc Dis. 2015 Aug;24(8):1823-31. doi: 10.1016/j.jstrokecerebrovasdis.2015.04.017. Epub 2015 May 18.
Subjective cognitive complaints (SCCs) are common after stroke, but detailed information about how SCCs differ between patients with stroke versus stroke-free individuals is not available. We evaluated the prevalence and profile of the 2 SCC components (content and worry) in patients 3 months after stroke versus controls using both a generic and a stroke-specific instrument.
Using a cross-sectional design, 142 patients were compared to 135 controls (matched at group level on age, sex, and estimate of premorbid intelligence quotient). SCC-content and SCC-worry were assessed using the Cognitive Failures Questionnaire (CFQ) and the Checklist of Cognitive and Emotional Consequences after stroke (CLCE-24). Univariate and multivariate linear (for continuous scores) and logistic (for dichotomous scores) regression analyses were used to explore differences between patients and controls on both instruments.
Based on the CLCE, patients reported more SCC-content (standardized β = .21, p.001) and SCC-worry (standardized β = .18, p.02) than controls in multivariate analyses. Profiles indicated that stroke was associated in particular with SCC-content on the domains of memory, attention, executive functioning, expressive language, and with attention-related SCC-worry. In contrast, no group differences were found on SCC-content and SCC-worry assessed by the CFQ.
The prevalence and profile of SCC-content and SCC-worry differ between patients and controls 3 months after stroke. The instrument used may, however, determine prevalence estimates. Stroke-specific inventories that differentiate between SCC-content and SCC-worry are preferable when attempting to determine SCC after stroke.
卒中后主观认知主诉（SCC）很常见，但关于卒中患者与未患卒中个体的SCC差异的详细信息尚不可知。我们使用通用和卒中特异性工具评估了卒中后3个月患者与对照组中SCC的两个组成部分（内容和担忧）的患病率及特征。
采用横断面设计，将142例患者与135名对照组（在年龄、性别和病前智商估计方面进行组间匹配）进行比较。使用认知失误问卷（CFQ）和卒中后认知与情感后果清单（CLCE - 24）评估SCC内容和SCC担忧。采用单变量和多变量线性（用于连续分数）及逻辑（用于二分法分数）回归分析来探讨两组在这两种工具上的差异。
基于CLCE，在多变量分析中，患者报告的SCC内容（标准化β = 0.21，p < 0.001）和SCC担忧（标准化β = 0.18，p = 0.02）均多于对照组。特征表明，卒中尤其与记忆、注意力、执行功能、表达性语言领域的SCC内容以及与注意力相关的SCC担忧相关。相比之下，通过CFQ评估的SCC内容和SCC担忧未发现组间差异。
卒中后3个月患者与对照组在SCC内容和SCC担忧的患病率及特征方面存在差异。然而，所使用的工具可能会影响患病率估计。在试图确定卒中后的SCC时，区分SCC内容和SCC担忧的卒中特异性量表更可取。
