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大麻购买任务的进一步验证。

Further validation of a marijuana purchase task.

作者信息

Aston Elizabeth R, Metrik Jane, MacKillop James

机构信息

Center for Alcohol and Addiction Studies, Brown University School of Public Health, Box G-S121-4, Providence, RI, 02912, USA.

Providence Veterans Affairs Medical Center, Providence, RI, 02908, USA; Center for Alcohol and Addiction Studies, Brown University School of Public Health, Box G-S121-4, Providence, RI, 02912, USA.

出版信息

Drug Alcohol Depend. 2015 Jul 1;152:32-8. doi: 10.1016/j.drugalcdep.2015.04.025. Epub 2015 May 11.

Abstract

BACKGROUND

A valid measure of the relative economic value of marijuana is needed to characterize individual variation in the drug's reinforcing value and inform evolving national marijuana policy. Relative drug value (demand) can be measured via purchase tasks, and demand for alcohol and cigarettes has been associated with craving, dependence, and treatment response. This study examined marijuana demand with a marijuana purchase task (MPT).

METHODS

The 22-item self-report MPT was administered to 99 frequent marijuana users (37.4% female, 71.5% marijuana use days, 15.2% cannabis dependent).

RESULTS

Pearson correlations indicated a negative relationship between intensity (free consumption) and age of initiation of regular use (r=-0.34, p<0.001), and positive associations with use days (r=0.26, p<0.05) and subjective craving (r=0.43, p<0.001). Omax (maximum expenditure) was positively associated with use days (r=0.29, p<0.01) and subjective craving (r=0.27, p<0.01). Income was not associated with demand. An exponential demand model provided an excellent fit to the data across users (R(2)=0.99). Group comparisons based on presence or absence of DSM-IV cannabis dependence symptoms revealed that users with any dependence symptoms showed significantly higher intensity of demand and more inelastic demand, reflecting greater insensitivity to price increases.

CONCLUSIONS

These results provide support for construct validity of the MPT, indicating its sensitivity to marijuana demand as a function of increasing cost, and its ability to differentiate between users with and without dependence symptoms. The MPT may denote abuse liability and is a valuable addition to the behavioral economic literature. Potential applications to marijuana pricing and tax policy are discussed.

摘要

背景

需要一种有效的方法来衡量大麻的相对经济价值,以描述该药物强化价值的个体差异,并为不断发展的国家大麻政策提供参考。相对药物价值(需求)可以通过购买任务来衡量,并且酒精和香烟的需求已与渴望、依赖和治疗反应相关联。本研究使用大麻购买任务(MPT)来检验大麻需求。

方法

对99名频繁使用大麻的使用者进行了包含22个项目的自报告MPT(37.4%为女性,71.5%有使用大麻的天数,15.2%对大麻有依赖)。

结果

皮尔逊相关性表明,强度(自由消费量)与开始经常使用大麻的年龄之间呈负相关(r = -0.34,p < 0.001),与使用天数呈正相关(r = 0.26,p < 0.05),与主观渴望呈正相关(r = 0.43,p < 0.001)。最大支出(Omax)与使用天数呈正相关(r = 0.29,p < 0.01),与主观渴望呈正相关(r = 0.27,p < 0.01)。收入与需求无关。指数需求模型对所有使用者的数据拟合良好(R² = 0.99)。基于是否存在DSM-IV大麻依赖症状的组间比较显示,有任何依赖症状的使用者表现出显著更高的需求强度和更缺乏弹性的需求,这反映出对价格上涨的敏感度更低。

结论

这些结果为MPT的结构效度提供了支持,表明其对大麻需求随成本增加的敏感性,以及区分有和没有依赖症状使用者的能力。MPT可能表示滥用倾向,是行为经济学文献中的一项有价值的补充。讨论了其在大麻定价和税收政策方面的潜在应用。

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