Trent Maria, Thompson Carol, Tomaszewski Kathy
Section on Adolescent Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Population, Family, and Reproductive Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
J Adolesc Health. 2015 Jul;57(1):100-6. doi: 10.1016/j.jadohealth.2015.03.008. Epub 2015 May 19.
To evaluate the feasibility, acceptability, and preliminary effectiveness of DepoText, a text messaging reminder system designed to improve moderately long-acting reversible contraception appointment attendance among young urban adolescent girls and young adult women using Depo-Provera.
Female patients aged 13-21 years willing to be randomized, using Depo-Provera, and owning a cell phone with text messaging were recruited from an urban academic practice in a community with high rates of unplanned pregnancy for this institutional review board-approved randomized controlled pilot trial. Participants completed a baseline Web-based survey and were followed for three injection cycles. Intervention participants received welcome, appointment, and healthy self-management messages using the Compliance for Life short messaging system platform over each injection cycle. Compliance for Life recorded outgoing and incoming communications, and patients were tracked for clinical behaviors. The log-transformed number of days between scheduled appointment and injection was analyzed using linear regression.
Recruitment data show 95% eligibility and 91% enrollment rates with maximum enrollment completion in 3 months. Most were African-American and resided in low-income, single-parent, and mother-headed households. Most participants had cell phone plans that included unlimited text messaging and Internet access and completed all three Depo-Provera cycles. Intervention participants returned closer to their scheduled appointments than their control peers for the first visit (Β = -.75; 95% confidence interval, -1.4 to .06; p = .03) but not for the second and third visits.
The DepoText intervention is acceptable, feasible, and shows short-term preliminary efficacy for improving clinic attendance for moderately long-acting reversible contraception appointments. Additional research exploring the cost and longitudinal prevention effectiveness is warranted.
评估DepoText的可行性、可接受性和初步有效性。DepoText是一种短信提醒系统,旨在提高使用醋酸甲羟孕酮的城市年轻少女和成年女性按时接受长效可逆避孕针剂注射的比例。
从一个意外怀孕率较高的社区的城市学术医疗机构招募年龄在13至21岁之间、愿意参与随机分组、正在使用醋酸甲羟孕酮且拥有可收发短信手机的女性患者,进行这项经机构审查委员会批准的随机对照试验性研究。参与者完成了一项基于网络的基线调查,并接受了三个注射周期的随访。干预组参与者在每个注射周期通过“生活依从性”短信系统平台接收欢迎、预约和健康自我管理信息。“生活依从性”记录了收发的信息,并对患者的临床行为进行跟踪。使用线性回归分析计划预约与注射之间天数的对数转换值。
招募数据显示,符合条件率为95%,入组率为91%,在3个月内完成了最大入组量。大多数参与者是非裔美国人,居住在低收入、单亲且以母亲为户主的家庭。大多数参与者的手机套餐包括无限短信和互联网接入,并完成了所有三个醋酸甲羟孕酮注射周期。干预组参与者在首次就诊时比对照组更接近预约时间(β = -0.75;95%置信区间,-1.4至0.06;p = 0.03),但在第二次和第三次就诊时并非如此。
DepoText干预是可接受的、可行的,并且在提高长效可逆避孕针剂注射门诊就诊率方面显示出短期初步疗效。有必要进行更多研究以探讨成本和长期预防效果。