Matsuda S, Uchida T
Rinsho Ketsueki. 1989 Aug;30(8):1261-5.
The mean intrasplenic blood cell transit time (STT), splenic blood cell volume (SV) and the slow mixing splenic blood cell volume (SSV) have been measured in normal subjects and patients with congestive and infiltrative splenomegaly. The normal red cell SV was 0.47 +/- 0.14 (mean +/- SD) % of the circulating red cell volume (RCV). In patients with congestive and infiltrative splenomegaly, SV was 9.82 +/- 3.55% and 0.96 +/- 0.71% of RCV, respectively. The SSV was 69.1 +/- 8.4% of the SV in normal subjects, but in patients with splenomegaly, its value was lower than that of normal SSV. The STT was 0.43 +/- 0.11 min. in normal subjects. In the patients with splenomegaly, it prolonged. But, the STT/SV and STT/SSV were rapid in patients with congestive splenomegaly and low in infiltrative splenomegaly. It seemed that SST/SV and STT/SSV were useful to distinguish between congestive and infiltrative splenomegaly. In the intrasplenic granulocyte kinetics, SV was similar to that of red cell. The STT was longer than that of red cell, in normal subjects and patients with splenomegaly. In the intrasplenic platelet kinetics, the ratio of cellular splenic volume to general circulation was the largest in platelets. The STT of platelet was the slowest in blood cells.
已对正常受试者以及充血性和浸润性脾肿大患者测量了脾内血细胞转运时间（STT）、脾血细胞容量（SV）和缓慢混合脾血细胞容量（SSV）。正常红细胞SV为循环红细胞容量（RCV）的0.47±0.14（均值±标准差）%。在充血性和浸润性脾肿大患者中，SV分别为RCV的9.82±3.55%和0.96±0.71%。正常受试者中SSV为SV的69.1±8.4%，但在脾肿大患者中，其值低于正常SSV。正常受试者的STT为0.43±0.11分钟。在脾肿大患者中，STT延长。但是，充血性脾肿大患者的STT/SV和STT/SSV较快，浸润性脾肿大患者的则较低。似乎STT/SV和STT/SSV有助于区分充血性和浸润性脾肿大。在脾内粒细胞动力学方面，SV与红细胞相似。在正常受试者和脾肿大患者中，STT比红细胞的长。在脾内血小板动力学方面，细胞脾容量与全身循环的比例在血小板中最大。血小板的STT在血细胞中是最慢的。
