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儿童精神病理学维度中的共病现象:来自行为遗传学的一致证据。

Comorbidity Among Dimensions of Childhood Psychopathology: Converging Evidence from Behavior Genetics.

作者信息

Rhee Soo Hyun, Lahey Benjamin B, Waldman Irwin D

机构信息

University of Colorado-Boulder.

University of Chicago.

出版信息

Child Dev Perspect. 2015 Mar 1;9(1):26-31. doi: 10.1111/cdep.12102.

Abstract

In this article, we review evidence from recent behavior genetic studies that examined the covariance among common childhood psychopathological conditions and tested specific hypotheses regarding common and broadband-specific underlying features of childhood psychopathology. Specifically, we review the distinction between internalizing and externalizing disorders, the support for the generalist genes and specialist environments model, negative emotionality as a heritable underlying feature common to both internalizing and externalizing disorders, and daring as a heritable broadband-specific underlying feature that distinguishes externalizing disorders from internalizing disorders. We also discuss the implications of research in the search for specific genes that influence childhood psychopathology and suggest avenues for new research.

摘要

在本文中,我们回顾了近期行为遗传学研究的证据,这些研究考察了常见儿童心理病理状况之间的协方差,并检验了关于儿童心理病理学常见和特定领域潜在特征的具体假设。具体而言,我们回顾了内化障碍和外化障碍之间的区别、对通才基因和专才环境模型的支持、消极情绪作为内化障碍和外化障碍共有的可遗传潜在特征,以及大胆作为区分外化障碍与内化障碍的可遗传特定领域潜在特征。我们还讨论了该研究在寻找影响儿童心理病理学的特定基因方面的意义,并提出了新的研究途径。

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