Salas Ariel A, Jerome Maggie L, Chandler-Laney Paula, Ambalavanan Namasivayam, Carlo Waldemar A
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, 35249, USA.
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, 35249, USA.
Pediatr Res. 2020 Nov;88(5):733-738. doi: 10.1038/s41390-020-1052-x. Epub 2020 Jul 7.
Clinicians could modify dietary interventions during early infancy by monitoring fat and fat-free mass accretion in very preterm infants.
Preterm infants were randomly assigned to either having reports on infant body composition available to the clinicians caring for them (intervention group) or not having reports available (control group). All infants underwent serial assessments of body composition by air-displacement plethysmography before 32 weeks of postmenstrual age (PMA) and at 36 weeks PMA. The primary outcome was percent body fat (%BF) at 3 months of corrected age (CA).
Fifty infants were randomized (median gestational age: 30 weeks; mean ± SD birth weight: 1387 ± 283 g). The mean %BF increased from 7 ± 4 before 32 weeks PMA to 20 ± 5 at 3 months CA. The differences in mean %BF between the intervention group and the control group were not statistically significant at 36 weeks PMA (14.5 vs. 13.6) or 3 months CA (20.8 vs. 19.4). Feeding practices and anthropometric measurements during hospitalization did not differ between groups.
Serial assessments of body composition in both intervention and control groups showed consistent increments in %BF. However, providing this information to clinicians did not influence nutritional practices or growth.
Serial assessments of body composition in preterm infants at 32 and 36 weeks postmenstrual age show consistent increments in % body fat up to 3 months of corrected age. However, providing this information to the clinician did not influence nutritional practices or growth.
临床医生可以通过监测极早产儿的脂肪和去脂体重增加情况，在婴儿早期调整饮食干预措施。
将早产儿随机分为两组，一组是为照顾他们的临床医生提供婴儿身体成分报告（干预组），另一组是不提供报告（对照组）。所有婴儿在孕龄（PMA）32周前和PMA 36周时通过空气置换体积描记法进行身体成分的系列评估。主要结局是矫正年龄（CA）3个月时的体脂百分比（%BF）。
50名婴儿被随机分组（中位胎龄：30周；平均±标准差出生体重：1387±283g）。平均%BF从PMA 32周前的7±4增加到CA 3个月时的20±5。干预组和对照组在PMA 36周时（14.5对13.6）或CA 3个月时（20.8对19.4）的平均%BF差异无统计学意义。两组住院期间的喂养方式和人体测量指标无差异。
干预组和对照组的身体成分系列评估均显示%BF持续增加。然而，向临床医生提供这些信息并未影响营养实践或生长情况。
对孕龄32周和36周的早产儿进行身体成分系列评估显示，直至矫正年龄3个月时，体脂百分比持续增加。然而，向临床医生提供这些信息并未影响营养实践或生长情况。
