López-Corella E, De León B, de Jonckheere J F
Bol Med Hosp Infant Mex. 1989 Sep;46(9):619-22.
A 13 year old boy died after a three day illness with severe headache, explosive vomiting, fever and progressive loss of consciousness. The autopsy revealed purulent and necrotizing meningoencephalitis mainly involving the basal regions and posterior fossa and on microscopic examination numerous trophozoites of Naegleria were seen in the meninges and necrotic brain tissue. The trophozoites were identified as Naegleria fowleri by immunoperoxidase staining. This case as well as others previously reported in Mexico and the documented presence of Naegleria species from several sources indicate that primary amebic meningoencephalitis should be considered in the differential diagnosis of cases with neurological symptoms of sudden onset.
一名13岁男孩在患病三天后死亡，其症状包括严重头痛、喷射性呕吐、发热及意识逐渐丧失。尸检显示为化脓性坏死性脑膜脑炎，主要累及脑底部区域和后颅窝，显微镜检查发现脑膜和坏死脑组织中有大量耐格里属滋养体。通过免疫过氧化物酶染色，这些滋养体被鉴定为福氏耐格里阿米巴。该病例以及墨西哥先前报道的其他病例，还有来自多个来源记录的耐格里属物种的存在，表明在对突然出现神经症状的病例进行鉴别诊断时，应考虑原发性阿米巴脑膜脑炎。
