墨西哥墨西卡利的5例原发性阿米巴脑膜脑炎：分离株研究

Lares-Villa F, De Jonckheere J F, De Moura H, Rechi-Iruretagoyena A, Ferreira-Guerrero E, Fernandez-Quintanilla G, Ruiz-Matus C, Visvesvara G S

Department of Microbiology, E.N.C.B., I.P.N., Carpio y Plan de Ayala, Col. Santo Tomás, Mexico, D.F.

J Clin Microbiol. 1993 Mar;31(3):685-8. doi: 10.1128/jcm.31.3.685-688.1993.

Five Naegleria strains isolated from patients with primary amebic meningoencephalitis and one strain isolated from the water of an artificial canal were investigated. All strains were pathogenic for mice when instilled intranasally and showed cytopathic effects in Vero cell cultures. Their growth characteristics (isolation and subculture at 45 degrees C), serological results, and isoenzyme patterns permitted us to identify the six strains as Naegleria fowleri. This is the first time that Naegleria fowleri has been isolated from patients with primary amebic meningoencephalitis in Mexico.

对从原发性阿米巴脑膜脑炎患者中分离出的5株耐格里属菌株以及从一条人工运河的水中分离出的1株菌株进行了研究。所有菌株经鼻内接种后对小鼠具有致病性，并在Vero细胞培养物中显示出细胞病变效应。它们的生长特性（在45摄氏度下分离和传代培养）、血清学结果和同工酶模式使我们能够将这6株菌株鉴定为福氏耐格里阿米巴。这是首次在墨西哥从原发性阿米巴脑膜脑炎患者中分离出福氏耐格里阿米巴。