Valenzuela G, López-Corella E, De Jonckheere J F
Trans R Soc Trop Med Hyg. 1984;78(4):558-9. doi: 10.1016/0035-9203(84)90084-1.
Primary meningoencephalitis caused by Naegleria fowleri was documented in a 16-year-old male from Mexicali in the state of Baja California in Mexico. In August 1978, seven days after sustaining moderate head trauma while swimming in a shallow, stagnant irrigation ditch on a hot summer day, the patient presented an acute illness with severe headache, fever and convulsions rapidly progressing into a comatose state. Actively moving trophozoites were observed in the spinal fluid on admission. The patient died shortly after admission to hospital on the third day of symptoms. Post-mortem examination revealed a meningoencephalitis with extensive destruction, haemorrhage and numerous parasites involving structures of the posterior fossa. Immunoperoxidase strains of trophozoites in meningeal and cerebellar tissue were positive for N. fowleri KUL and negative for N. gruberi, N. australiensis and Acanthamoeba rhysodes. This appears to be the first documented case of the disease in Mexico.
墨西哥下加利福尼亚州墨西卡利市一名16岁男性被确诊为由福氏耐格里阿米巴引起的原发性脑膜脑炎。1978年8月，在炎热夏日于一条浅而静止的灌溉沟渠游泳时遭受中度头部创伤七天后，患者出现急性病症，伴有严重头痛、发热和抽搐，并迅速发展为昏迷状态。入院时在脑脊液中观察到活跃移动的滋养体。患者在出现症状第三天入院后不久死亡。尸检显示为脑膜脑炎，伴有广泛破坏、出血以及累及后颅窝结构的大量寄生虫。脑膜和小脑组织中滋养体的免疫过氧化物酶染色对福氏耐格里阿米巴KUL呈阳性，而对格氏耐格里阿米巴、澳洲耐格里阿米巴和里斯棘阿米巴呈阴性。这似乎是墨西哥该疾病的首例记录病例。
