Bove Joanna M, Golden Matthew R, Dhanireddy Shireesha, Harrington Robert D, Dombrowski Julia C
*Center for AIDS and STD, University of Washington, Seattle, WA; †Department of Medicine, University of Washington, Seattle, WA; ‡Public Health-Seattle & King County HIV/STD Program, Seattle, WA; and §Department of Epidemiology, University of Washington, Seattle, WA.
J Acquir Immune Defic Syndr. 2015 Nov 1;70(3):262-8. doi: 10.1097/QAI.0000000000000707.
Improving patient retention in HIV care is crucial to improving the HIV care continuum. We instituted and evaluated a relinkage program that uses clinical data to identify potentially out-of-care patients, matches those data to public health surveillance, and employs a linkage specialist (LS) to coordinate care relinkage.
The intervention began November 1, 2012, in the largest HIV clinic in Washington State. We evaluated program outcomes and compared patient outcomes in the year after initiation of the intervention to a historical control cohort of patients. Cox proportional hazard ratios were used to compare time to relinkage to care between cohorts, and regression models using generalized estimated equations were preformed to examine secondary outcomes of relinkage to care, engagement in care, and viral suppression.
A total of 753 patients were identified as "out of care" on November 1, 2012. Matching with surveillance data and initial LS investigations found that 596 (79%) of these patients had moved, transferred care, or were incarcerated. Of the 157 remaining patients, 40 (25%) relinked to care before LS contact, and the LS successfully contacted 38 (24%). A total of 116 (15%) patients in the intervention cohort relinked to care and 24 (20%) were contacted by the LS. Compared with the historical cohort, the time to relinkage was shorter among patients in the intervention cohort [adjusted hazard ratio = 1.7 (1.2-2.3)] and a greater proportion relinked (15% vs. 10%).
This clinic-based surveillance-informed relinkage intervention showed statistically significant but modest effectiveness in returning out-of-care patients to HIV care compared with historical controls.
提高艾滋病毒护理中的患者留存率对于改善艾滋病毒护理连续过程至关重要。我们设立并评估了一项重新联系项目,该项目利用临床数据识别可能失访的患者,将这些数据与公共卫生监测数据进行匹配,并聘请一名联系专员(LS)来协调护理重新联系工作。
干预措施于2012年11月1日在华盛顿州最大的艾滋病毒诊所启动。我们评估了项目成果,并将干预措施启动后一年的患者结果与一个历史对照患者队列进行了比较。使用Cox比例风险比来比较队列之间重新联系到护理的时间,并使用广义估计方程进行回归模型分析,以检查重新联系到护理、参与护理和病毒抑制的次要结果。
2012年11月1日,共有753名患者被确定为“失访”。与监测数据匹配以及联系专员的初步调查发现,这些患者中有596名(79%)已经搬家、转移了护理或被监禁。在剩下的157名患者中,40名(25%)在联系专员接触之前就重新联系到了护理,联系专员成功联系到了38名(24%)。干预队列中共有116名(15%)患者重新联系到了护理,联系专员联系到了24名(20%)。与历史队列相比,干预队列中的患者重新联系到护理的时间更短[调整后的风险比 = 1.7(1.2 - 2.3)],重新联系的比例更高(15%对10%)。
与历史对照相比,这项基于诊所监测的重新联系干预措施在让失访患者重新接受艾滋病毒护理方面显示出统计学上显著但适度的效果。