Lee Andrew, Fischer Gayle
Department of Dermatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Northern Clinical School, University of Sydney, St Leonards, New South Wales, Australia.
Australas J Dermatol. 2015 Aug;56(3):192-6. doi: 10.1111/ajd.12362. Epub 2015 Jun 16.
Hidradenitis suppurativa (HS) is an uncommon chronic skin condition that can range in severity from a single nodule to extensive disease and can have a profound effect on quality of life. Anti-androgen medication has been suggested as a possible management strategy in female patients with HS and is mentioned in review articles as a treatment option. Despite this, there is limited literature documenting the use of anti-androgens in HS. We present our experience with 20 patients with HS treated with oral spironolactone. We advocate spironolactone as a useful, low-cost first-line treatment for women with HS, with relatively few side-effects.
化脓性汗腺炎(HS)是一种罕见的慢性皮肤病,严重程度从单个结节到广泛性病变不等,会对生活质量产生深远影响。抗雄激素药物已被提议作为女性HS患者的一种可能治疗策略,并且在综述文章中被提及为一种治疗选择。尽管如此,关于抗雄激素药物在HS中的应用的文献有限。我们介绍了20例接受口服螺内酯治疗的HS患者的经验。我们主张螺内酯作为一种有用、低成本的一线治疗药物,用于治疗女性HS患者,且副作用相对较少。