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一组20例接受螺内酯治疗的化脓性汗腺炎女性病例。

A case series of 20 women with hidradenitis suppurativa treated with spironolactone.

作者信息

Lee Andrew, Fischer Gayle

机构信息

Department of Dermatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Northern Clinical School, University of Sydney, St Leonards, New South Wales, Australia.

出版信息

Australas J Dermatol. 2015 Aug;56(3):192-6. doi: 10.1111/ajd.12362. Epub 2015 Jun 16.

Abstract

Hidradenitis suppurativa (HS) is an uncommon chronic skin condition that can range in severity from a single nodule to extensive disease and can have a profound effect on quality of life. Anti-androgen medication has been suggested as a possible management strategy in female patients with HS and is mentioned in review articles as a treatment option. Despite this, there is limited literature documenting the use of anti-androgens in HS. We present our experience with 20 patients with HS treated with oral spironolactone. We advocate spironolactone as a useful, low-cost first-line treatment for women with HS, with relatively few side-effects.

摘要

化脓性汗腺炎(HS)是一种罕见的慢性皮肤病,严重程度从单个结节到广泛性病变不等,会对生活质量产生深远影响。抗雄激素药物已被提议作为女性HS患者的一种可能治疗策略,并且在综述文章中被提及为一种治疗选择。尽管如此,关于抗雄激素药物在HS中的应用的文献有限。我们介绍了20例接受口服螺内酯治疗的HS患者的经验。我们主张螺内酯作为一种有用、低成本的一线治疗药物,用于治疗女性HS患者,且副作用相对较少。

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