Mendoza-Pinto C, Méndez-Martínez S, Soto-Santillán P, Galindo Herrera J, Pérez-Contreras I, Macías-Díaz S, Taboada-Cole A, García-Carrasco M
Systemic Autoimmune Diseases Research Unit, IMSS, Puebla, México Department of Rheumatology and Immunology, Benemérita Universidad Autónoma de Puebla, Puebla, México
Systemic Autoimmune Diseases Research Unit, IMSS, Puebla, México.
Lupus. 2015 Oct;24(11):1227-32. doi: 10.1177/0961203315591621. Epub 2015 Jun 17.
The objective of this cross-sectional study was to determine relationships between socioeconomic status and organ damage in Mexican systemic lupus erythematosus (SLE) patients. Demographic and clinical variables were assessed. Socioeconomic status was evaluated using the Graffar method and monthly household income. Lupus activity and organ damage were measured using the SLE disease activity scale, validated for the Mexican population (Mex-SLEDAI), and the Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) scale. The 143 Mexican female SLE patients included (mean age 40.1 ± 8.9 years, mean disease duration 8.9 ± 6.3 years) had a mean monthly household income of $ 407.2 ± 326.5. According to the Graffar index, 18.9%, 52.5%, and 28.7% had high/medium-high, medium, and medium-low/low socioeconomic status, respectively. Organ damage was observed in 61 patients (42.7%). Patients with organ damage had lower monthly household incomes ($241.4 ± 152.4 vs. $354.8 ± 288.3) and were more frequently unemployed (57.3% vs. 35.3%; p = 0.01) than those without. Low monthly income was not associated with lupus activity or self-reported health status. In the adjusted multivariate analysis, low monthly income ( < $300) was associated with organ damage. In conclusion, low income may be associated with organ damage in Mexican SLE patients.
这项横断面研究的目的是确定墨西哥系统性红斑狼疮（SLE）患者的社会经济地位与器官损害之间的关系。评估了人口统计学和临床变量。使用格拉法尔方法和家庭月收入评估社会经济地位。使用针对墨西哥人群验证的SLE疾病活动量表（Mex-SLEDAI）和系统性红斑狼疮国际协作诊所/美国风湿病学会（SLICC/ACR）量表测量狼疮活动和器官损害。纳入的143名墨西哥女性SLE患者（平均年龄40.1±8.9岁，平均病程8.9±6.3年）家庭月收入平均为407.2±326.5美元。根据格拉法尔指数，分别有18.9%、52.5%和28.7%的患者具有高/中高、中、中低/低社会经济地位。61名患者（42.7%）出现器官损害。与未出现器官损害的患者相比，出现器官损害的患者家庭月收入较低（241.4±152.4美元对354.8±288.3美元），且失业频率更高（57.3%对35.3%；p=0.01）。低月收入与狼疮活动或自我报告的健康状况无关。在调整后的多变量分析中，低月收入（<300美元）与器官损害相关。总之，低收入可能与墨西哥SLE患者的器官损害有关。
