Wouters E F, Verschoof A C, Polko A H, Visser B F
Department of Pulmonary Diseases, University Limburg, Maastricht, The Netherlands.
Respir Med. 1989 Jul;83(4):309-13. doi: 10.1016/s0954-6111(89)80202-1.
Impedance measurements of the respiratory system by means of the forced oscillation technique were performed in a group of 20 COPD patients before and after inhalation of 0.400 mg salbutamol. A slight, but statistically non significant decrease of resistance is observed at all frequencies from 12 to 52 Hz. Increase of reactance values reached a statistically significant level at all frequencies except at 24 and 52 Hz. It is hypothesized that the increase of reactance in these patients can be explained by an increase of capacitance due to an increase of airway compliance or a decrease of peripheral resistance according to Mead's analogon of the lungs.
采用强迫振荡技术对一组20例慢性阻塞性肺疾病（COPD）患者在吸入0.400mg沙丁胺醇前后进行呼吸系统阻抗测量。在12至52Hz的所有频率下均观察到阻力有轻微下降，但在统计学上无显著意义。除24Hz和52Hz外，在所有频率下电抗值的增加均达到统计学显著水平。据推测，根据米德的肺类比，这些患者电抗的增加可由气道顺应性增加或外周阻力降低导致的电容增加来解释。
