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中药的可追溯性与质量控制:从化学指纹图谱到二维条形码

Traceability and Quality Control in Traditional Chinese Medicine: From Chemical Fingerprint to Two-Dimensional Barcode.

作者信息

Cai Yong, Li Xiwen, Li Mei, Chen Xiaojia, Hu Hao, Ni Jingyun, Wang Yitao

机构信息

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau ; Information Technology College of Beijing Normal University, Zhuhai Campus, Zhuhai 519087, China.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau ; Research Center for Pharmacognosy, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Evid Based Complement Alternat Med. 2015;2015:251304. doi: 10.1155/2015/251304. Epub 2015 May 18.

DOI:10.1155/2015/251304
PMID:26089936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4451286/
Abstract

Chemical fingerprinting is currently a widely used tool that enables rapid and accurate quality evaluation of Traditional Chinese Medicine (TCM). However, chemical fingerprints are not amenable to information storage, recognition, and retrieval, which limit their use in Chinese medicine traceability. In this study, samples of three kinds of Chinese medicines were randomly selected and chemical fingerprints were then constructed by using high performance liquid chromatography. Based on chemical data, the process of converting the TCM chemical fingerprint into two-dimensional code is presented; preprocess and filtering algorithm are also proposed aiming at standardizing the large amount of original raw data. In order to know which type of two-dimensional code (2D) is suitable for storing data of chemical fingerprints, current popular types of 2D codes are analyzed and compared. Results show that QR Code is suitable for recording the TCM chemical fingerprint. The fingerprint information of TCM can be converted into data format that can be stored as 2D code for traceability and quality control.

摘要

化学指纹图谱是目前广泛应用的一种工具,可实现对中药的快速、准确质量评价。然而,化学指纹图谱不便于信息存储、识别和检索,这限制了它们在中药溯源中的应用。本研究随机选取了三种中药的样本,然后采用高效液相色谱法构建化学指纹图谱。基于化学数据,提出了将中药化学指纹图谱转换为二维码的过程;还提出了预处理和滤波算法,旨在对大量原始数据进行标准化。为了了解哪种类型的二维码适用于存储化学指纹图谱数据,对当前流行的二维码类型进行了分析和比较。结果表明,二维码适用于记录中药化学指纹图谱。中药的指纹信息可以转换为可存储为二维码的数据格式,用于溯源和质量控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f46c/4451286/6bdc1663963b/ECAM2015-251304.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f46c/4451286/6bdc1663963b/ECAM2015-251304.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f46c/4451286/6bdc1663963b/ECAM2015-251304.001.jpg

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