Oling Michael, Odongo J, Kituuka O, Galukande M
Department of Surgery, College of Health Sciences, Makerere University, P. O. Box 7072, Kampala, Uganda.
BMC Res Notes. 2015 Jun 23;8:256. doi: 10.1186/s13104-015-1184-y.
More than half of the world's population is infected with Helicobacter pylori (H. pylori), the primary cause of chronic gastritis. Chronic gastritis is associated with peptic ulcer and in advanced stages with an increased risk of developing gastric adenocarcinoma. In many developing countries access to upper gastrointestinal (UGI) endoscopy services is limited. As a result, many UGI diseases are treated empirically.
To determine the prevalence of H. pylori in patients presenting with dyspepsia, and the mean time from onset of symptoms to performing an endoscopy examination.
A cross sectional descriptive study conducted from 5th January to 30th April 2014. Adult patients with dyspepsia who were referred for UGI endoscopy were recruited consecutively. Questionnaires were used to collect data which were analyzed using STATA software. IRB approval was obtained.
In total, 111 participants' data were analyzed. The F:M ratio was 1:1.4, mean age 43 years (SD = 16). The prevalence of H. pylori gastritis was 36%. The minimum time to endoscopy was 3 weeks, maximum 1,248 weeks and the mean time 57 weeks.
The burden of H. pylori infection in patients with dyspepsia was high. Patients had prior empirical antibiotic therapy. Access to endoscopic services is limited.
全球一半以上的人口感染幽门螺杆菌（H. pylori），这是慢性胃炎的主要病因。慢性胃炎与消化性溃疡相关，在晚期会增加患胃腺癌的风险。在许多发展中国家，上消化道（UGI）内镜检查服务的可及性有限。因此，许多UGI疾病都是经验性治疗。
确定消化不良患者中幽门螺杆菌的患病率，以及从症状出现到进行内镜检查的平均时间。
于2014年1月5日至4月30日进行了一项横断面描述性研究。连续招募因UGI内镜检查而转诊的成年消化不良患者。使用问卷收集数据，并使用STATA软件进行分析。获得了机构审查委员会（IRB）的批准。
总共分析了111名参与者的数据。男女比例为1:1.4，平均年龄43岁（标准差=16）。幽门螺杆菌胃炎的患病率为36%。内镜检查的最短时间为3周，最长为1248周，平均时间为57周。
消化不良患者中幽门螺杆菌感染的负担很高。患者曾接受经验性抗生素治疗。内镜检查服务的可及性有限。
