Mbale Regional Referral Hospital, P.O. Box 921, Mbale, Uganda.
Lira Regional Referral Hospital, Plot 9/19, 21-41 Ngetta Road Police Rd, Lira P.O.BOX 2, Lira, Uganda.
Afr Health Sci. 2021 Jun;21(2):919-926. doi: 10.4314/ahs.v21i2.54.
Endoscopy is required for formal diagnosis of many upper gastrointestinal (UGI) conditions including oesophageal cancer (OC). There is a paucity of data on endoscopy findings in East Africa as access to testing is challenging for patients. We describe the findings of 10 years of UGI endoscopy in Mbale Regional Referral Hospital (MRRH).
Records of patients that underwent UGI endoscopy in MRRH, November 2009 - March 2019 were retrospectively analysed. Indication, macroscopic findings, histology and patient demographics were retrieved. Sub-group analyses were performed on those with a histological diagnosis of oesophageal cancer.
833 eligible patients received single UGI procedures during the study period. Mean age was 54.8 years, range 16-93 years and 56.9% of patients were male. The main indication was dysphagia (42%) and the most common findings OC (34%) and gastritis (28%). 151 patients had histologically proven OC with a median age of 60 years and a 2:1 male to female ratio. 145/151 (96%) of samples tested revealed squamous cell carcinoma (SCC).
Those undergoing endoscopy in MRRH are most commonly male patients presenting in their 5th decade with dysphagia. There is a high proportion of significant findings including gastritis, peptic ulcer disease, and oesophageal cancer.
许多上消化道（UGI）疾病的正式诊断都需要进行内镜检查，包括食道癌（OC）。由于东非地区的患者难以获得检测，因此有关内镜检查结果的数据很少。我们描述了 Mbale 地区转诊医院（MRRH）10 年来 UGI 内镜检查的结果。
回顾性分析了 2009 年 11 月至 2019 年 3 月期间在 MRRH 接受 UGI 内镜检查的患者的记录。提取了检查的适应症、肉眼观察结果、组织学和患者人口统计学资料。对那些有组织学诊断为食道癌的患者进行了亚组分析。
在研究期间，833 名符合条件的患者接受了单次 UGI 检查。平均年龄为 54.8 岁，范围为 16-93 岁，其中 56.9%为男性。主要适应症为吞咽困难（42%），最常见的发现为食道癌（34%）和胃炎（28%）。151 名患者经组织学证实为食道癌，中位年龄为 60 岁，男女比例为 2:1。145/151（96%）例样本检测出鳞状细胞癌（SCC）。
在 MRRH 接受内镜检查的患者主要是 50 多岁的男性，以吞咽困难为主要症状。有很大比例的重要发现，包括胃炎、消化性溃疡病和食道癌。
