Aslani Abolfazl, Rostami Farnaz
Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran ; Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2015 Apr;20(4):403-11.
New formulations and technologies have been developed through oral drug delivery systems' researches. Such researches display significance of oral route amongst patients. We've reviewed all the features associated with medicated chewing gum as a modern drug delivery by introducing the history, advantages and disadvantages, methods of manufacturing, composition differences, evaluation tests and examples of varieties of medicated chewing gums. Acceptance of medicated chewing gum has been augmented through years. The advantages and therapeutic benefits of chewing gum support its development as we can see new formulations with new drugs contained have been produced from past and are going to find a place in market by formulation of new medicated chewing gums. Potential applications of medicated chewing gums are highly widespread as they will be recognized in future. Nowadays standards for qualifying chewing gums are the same as tablets. Patient-centered studies include medicated chewing gums as a delivery system too which creates compliance for patients.
通过口服给药系统的研究,已经开发出了新的制剂和技术。这类研究显示了口服途径在患者中的重要性。通过介绍药用口香糖作为一种现代药物递送方式的历史、优缺点、制造方法、成分差异、评估测试以及各类药用口香糖的实例,我们回顾了与药用口香糖相关的所有特性。多年来,药用口香糖的接受度一直在提高。口香糖的优点和治疗益处支持了其发展,因为我们可以看到,过去已经生产出了含有新药的新制剂,并且通过新药用口香糖的配方,它们将在市场上占据一席之地。药用口香糖的潜在应用非常广泛,因为它们在未来将会得到认可。如今,口香糖的质量标准与片剂相同。以患者为中心的研究也将药用口香糖作为一种递送系统,这提高了患者的依从性。