Natasha Khurshid, Hussain Akhtar, Azad Khan A K, Bhowmik Bishwajit
Institute of Health and Society, Section for International Health, University of Oslo, Oslo, Norway. ; Bangladesh University of Health Sciences, Diabetic Association of Bangladesh, Dhaka, Bangladesh.
Institute of Health and Society, Section for International Health, University of Oslo, Oslo, Norway.
Diabetes Metab J. 2015 Jun;39(3):218-29. doi: 10.4093/dmj.2015.39.3.218. Epub 2015 May 6.
Depression and glucose abnormality are increasing in Bangladesh including its rural area. This study was designed to determine the prevalence of depression in an urbanizing rural population of Bangladesh with or without glucose abnormality (including diabetes mellitus [DM], and pre-diabetes which combines impaired fasting glucose and impaired glucose tolerance pre-DM).
A total of 2,293 subjects aged ≥20 years were investigated. Sociodemographic and anthropometric details, blood pressure, fasting (fasting plasma glucose) and 2 hours after 75 g plasma glucose (2-hour plasma glucose), were studied. Montgomery-Asberg Depression Rating Scale was used to assess depression.
The overall prevalence of DM was 7.9% and pre-DM was 8.6%. Prevalence of depression was 15.31% (n=351; 95% confidence interval [CI], 1.59 to 1.36) with mean depressive score 17.62±3.49. Female were more likely to have depression (17.16%). The 22.35% of male and 29.46% of female with pre-DM and 26.58% male and 36.27% female with DM had depressive symptoms. There was no significant variation in the mean age of different groups (healthy, depressed and with glucose abnormality). Depression was significantly associated with age, marital status, occupation, high physical activity, and low body mass index. The odds ratio (OR) for depression was significantly increased in patients with glucose abnormality compared with those without pre-DM (OR, 2.49; 95% CI, 1.76 to 3.51; P<0.000) and DM (OR, 3.27; 95% CI, 2.33 to 4.60; P<0.000).
Prevalence of depression found alarming in our study area though lesser than previous studies and it is significantly related to glucose abnormality. The study reveals that mental health should get more focused specially along with metabolic diseases.
在孟加拉国，包括农村地区在内，抑郁症和血糖异常的情况正在增加。本研究旨在确定孟加拉国一个正在城市化的农村人口中，有或无血糖异常（包括糖尿病[DM]以及合并空腹血糖受损和糖耐量受损的糖尿病前期）的抑郁症患病率。
共调查了2293名年龄≥20岁的受试者。研究了社会人口统计学和人体测量学细节、血压、空腹血糖（空腹血浆葡萄糖）以及75克葡萄糖负荷后2小时的血糖（2小时血浆葡萄糖）。使用蒙哥马利-阿斯伯格抑郁评定量表评估抑郁症。
DM的总体患病率为7.9%，糖尿病前期为8.6%。抑郁症患病率为15.31%（n = 351；95%置信区间[CI]，1.59至1.36），平均抑郁评分为17.62±3.49。女性患抑郁症的可能性更高（17.16%）。糖尿病前期男性中有22.35%、女性中有29.46%有抑郁症状，糖尿病男性中有26.58%、女性中有36.27%有抑郁症状。不同组（健康、抑郁和血糖异常）的平均年龄没有显著差异。抑郁症与年龄、婚姻状况、职业、高体力活动和低体重指数显著相关。与无糖尿病前期的患者相比，血糖异常患者患抑郁症的比值比（OR）显著升高（OR，2.49；95%CI，1.76至3.51；P<0.000），与糖尿病患者相比也显著升高（OR，3.27；95%CI，2.33至4.60；P<0.000）。
尽管本研究区域的抑郁症患病率低于先前研究，但仍令人担忧，且与血糖异常显著相关。该研究表明，心理健康应得到更多关注，尤其是与代谢疾病相关的方面。
