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皮肤胶原性血管病:全身性皮肤毛细血管扩张的罕见病因。

Cutaneous collagenous vasculopathy: a rare cause of generalised cutaneous telangiectasia.

作者信息

Toda-Brito Helena, Resende Cristina, Catorze Goreti, Viana Isabel

机构信息

Dermatology Department, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.

Dermatology Department, Hospital de Braga, Braga, Portugal.

出版信息

BMJ Case Rep. 2015 Jul 8;2015:bcr2015210635. doi: 10.1136/bcr-2015-210635.

Abstract

Cutaneous collagenous vasculopathy is a rare cutaneous microangiopathy of unknown aetiology with only 27 cases reported to date. It is characterised clinically by generalised cutaneous telangiectasias and microscopically by dilation and marked thickening of the walls of superficial dermal blood vessels. Differential diagnosis should be performed with other causes of disseminated telangiectasias, including generalised essential telangiectasia, from which it is clinically indistinguishable. We report a new case of cutaneous collagenous vasculopathy in a 61-year-old woman presenting with a 5-year history of asymptomatic telangiectasias distributed symmetrically on her upper and lower limbs and highlight the importance of clinicopathological correlation for the diagnosis of this disease.

摘要

皮肤胶原性血管病是一种病因不明的罕见皮肤微血管病,迄今为止仅有27例报道。其临床特征为全身性皮肤毛细血管扩张,镜下表现为真皮浅层血管壁扩张和显著增厚。应与其他导致弥漫性毛细血管扩张的病因进行鉴别诊断,包括全身性特发性毛细血管扩张,临床上难以将二者区分开来。我们报告了一例61岁女性的皮肤胶原性血管病新病例,该患者有5年无症状性毛细血管扩张病史,病变对称分布于上下肢,并强调了临床病理相关性对该病诊断的重要性。

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