Fendrich Michael, Fuhrmann Daniel, Berger Lisa, Plate Charles, Lewis Douglas, Jones Joseph
School of Social Work University of Connecticut West Hartford, Connecticut USA.
Center for Applied Behavioral Health Research University of Wisconsin-Milwaukee Milwaukee, Wisconsin USA.
Addict Behav. 2015 Nov;50:213-6. doi: 10.1016/j.addbeh.2015.06.028. Epub 2015 Jun 11.
Researchers have increasingly used collateral informants to validate the reports provided by primary research subjects. We assessed the utility of collateral informants for college students in a study that incorporates biomarkers to validate student reports of recent drinking behavior.
Students from a Midwestern university were randomly selected for a study in which they provided 90-day Timeline Followback data, hair and fingernail specimens for ethylglucuronide (EtG) testing, and information about collateral (friends or peers) informants who were familiar with their drinking behavior. We compared summary measures of recent drinking to collateral informant reports for the subset of 72 students who were selected to participate in the collateral validation process who had complete measures. Kappa, weighted kappa, and McNemar tests were performed to evaluate levels of agreement. We compared levels of use indicated by each informant within the context of EtG findings. We also compared respondent and collateral reports with respect to heavy drinking directly to EtG test results.
There was considerable overlap between the reports provided by the student participants and their collateral informants. Within the context of EtG-informed analyses, collaterals rarely provided new information about heavy use beyond that provided by the study subjects.
Collateral informants have limited utility in non-clinical studies of heavy drinking in randomly selected college students.
研究人员越来越多地使用旁证信息提供者来验证主要研究对象提供的报告。在一项纳入生物标志物以验证学生近期饮酒行为报告的研究中,我们评估了旁证信息提供者对大学生的效用。
从一所中西部大学随机挑选学生参与一项研究,他们需提供90天时间线追溯数据、用于乙基葡萄糖醛酸苷(EtG)检测的头发和指甲样本,以及有关熟悉其饮酒行为的旁证(朋友或同龄人)信息提供者的信息。对于被选入旁证验证过程且有完整测量数据的72名学生子集,我们将近期饮酒的汇总指标与旁证信息提供者的报告进行了比较。进行了卡方检验、加权卡方检验和 McNemar 检验以评估一致性水平。我们在EtG检测结果的背景下比较了每个信息提供者指出的使用水平。我们还将受访者和旁证关于重度饮酒的报告直接与EtG检测结果进行了比较。
学生参与者及其旁证信息提供者提供的报告之间存在相当大的重叠。在基于EtG的分析背景下,旁证很少能提供超出研究对象所提供的关于重度饮酒的新信息。
在随机挑选的大学生重度饮酒非临床研究中,旁证信息提供者的效用有限。