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高分辨率变形单光子发射计算机断层显像

High-Resolution Anamorphic SPECT Imaging.

作者信息

Durko Heather L, Barrett Harrison H, Furenlid Lars R

机构信息

Department of Medical Imaging, Center for Gamma-Ray Imaging, University of Arizona, Tucson, AZ 85724 USA, and the College of Optical Sciences, University of Arizona, Tucson, AZ 85721 USA.

出版信息

IEEE Trans Nucl Sci. 2014 Jun;61(3):1126-1135. doi: 10.1109/TNS.2014.2304853.

DOI:10.1109/TNS.2014.2304853
PMID:26160983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4494124/
Abstract

We have developed a gamma-ray imaging system that combines a high-resolution silicon detector with two sets of movable, half-keel-edged copper-tungsten blades configured as crossed slits. These apertures can be positioned independently between the object and detector, producing an anamorphic image in which the axial and transaxial magnifications are not constrained to be equal. The detector is a 60 mm × 60 mm, one-millimeter-thick, one-megapixel silicon double-sided strip detector with a strip pitch of 59 m. The flexible nature of this system allows the application of adaptive imaging techniques. We present system details; calibration, acquisition, and reconstruction methods; and imaging results.

摘要

我们开发了一种伽马射线成像系统,该系统将高分辨率硅探测器与两组配置成交叉狭缝的可移动半龙骨边缘铜钨叶片相结合。这些孔径可以独立地位于物体和探测器之间,产生一种变形图像,其中轴向和横向放大倍数不受限于相等。探测器是一个60毫米×60毫米、厚1毫米、100万像素的硅双面条形探测器,条间距为59微米。该系统的灵活性允许应用自适应成像技术。我们展示了系统细节、校准、采集和重建方法以及成像结果。

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Adaptive SPECT imaging with crossed-slit apertures.采用交叉狭缝孔径的自适应单光子发射计算机断层扫描成像。
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本文引用的文献

1
Data-Processing Strategies for Crossed-Strip Gamma-Ray Detectors.交叉条带伽马射线探测器的数据处理策略
IEEE Nucl Sci Symp Conf Rec (1997). 2008 Oct;2008:4091-4094. doi: 10.1109/NSSMIC.2008.4774181.
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Performance Characteristics of Thick Silicon Double-sided Strip Detectors.厚硅双面条形探测器的性能特性
IEEE Nucl Sci Symp Conf Rec (1997). 2007 Oct-Nov;2007:1656-1660. doi: 10.1109/NSSMIC.2007.4437318.
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Fast maximum-likelihood estimation methods for scintillation cameras and other optical sensors.用于闪烁相机和其他光学传感器的快速最大似然估计方法。
Proc SPIE Int Soc Opt Eng. 2007 Aug 26;6707. doi: 10.1117/12.740321.
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High-resolution, anamorphic, adaptive small-animal SPECT imaging with silicon double-sided strip detectors.
Proc SPIE Int Soc Opt Eng. 2011 Aug 21;8143. doi: 10.1117/12.896729.
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A System Calibration and Fast Iterative Reconstruction Method for Next-Generation SPECT Imagers.一种用于下一代单光子发射计算机断层显像(SPECT)成像仪的系统校准和快速迭代重建方法。
IEEE Trans Nucl Sci. 2012 Oct;59(5):1990-1996. doi: 10.1109/TNS.2012.2198243.
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SPECT detectors: the Anger Camera and beyond.单光子发射型计算机断层扫描仪探测器:从安格相机到更先进的技术。
Phys Med Biol. 2011 Sep 7;56(17):R145-82. doi: 10.1088/0031-9155/56/17/R01. Epub 2011 Aug 9.
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Evaluation of a multi-pinhole collimator for imaging small animals with different sizes.评估一种多针孔准直器在对不同大小小动物成像中的应用。
Mol Imaging Biol. 2012 Feb;14(1):60-9. doi: 10.1007/s11307-011-0472-8.
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System Integration of FastSPECT III, a Dedicated SPECT Rodent-Brain Imager Based on BazookaSPECT Detector Technology.基于巴祖卡单光子发射计算机断层扫描(BazookaSPECT)探测器技术的专用单光子发射计算机断层扫描(SPECT)啮齿动物脑成像仪FastSPECT III的系统集成。
IEEE Nucl Sci Symp Conf Rec (1997). 2009 Nov 1;Oct. 24 2009-Nov. 1 2009:4004-4008. doi: 10.1109/NSSMIC.2009.5401924.
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Multi-pinhole SPECT Imaging with Silicon Strip Detectors.基于硅条探测器的多针孔单光子发射计算机断层成像
IEEE Trans Nucl Sci. 2009 Jun 16;56(3):646-652. doi: 10.1109/TNS.2009.2012514.
10
Maximum-Likelihood Estimation With a Contracting-Grid Search Algorithm.基于收缩网格搜索算法的最大似然估计
IEEE Trans Nucl Sci. 2010 Jun 1;57(3):1077-1084. doi: 10.1109/TNS.2010.2045898.