Baron-Cohen Simon, Wheelwright Sally, Burtenshaw Amy, Hobson Esther
Department of Psychiatry, Autism Research Centre, Cambridge University, Douglas House, 18b Trumpington Rd., Cambridge, CB2 8AH, UK.
Hum Nat. 2007 Jun;18(2):125-31. doi: 10.1007/s12110-007-9014-0. Epub 2007 Jul 3.
A total of 378 mathematics undergraduates (selected for being strong at "systemizing") and 414 students in other (control) disciplines at Cambridge University were surveyed with two questions: (1) Do you have a diagnosed autism spectrum condition? (2) How many relatives in your immediate family have a diagnosed autism spectrum condition? Results showed seven cases of autism in the math group (or 1.85%) vs one case of autism in the control group (or 0.24%), a ninefold difference that is significant. Controlling for sex and general population sampling, this represents a three- to sevenfold increase for autism spectrum conditions among the mathematicians. There were 7 of 1,405 (or 0.5%) cases of autism in the immediate families of the math group vs 2 of 1,669 (or 0.1%) cases in the immediate families of the control group, which again is a significant difference. These results confirm a link between autism and systemizing, and they suggest this link is genetic given the association between autism and first-degree relatives of mathematicians.
研究人员对剑桥大学的378名数学专业本科生(因“系统化”能力强而入选)和414名其他(对照)学科的学生进行了两个问题的调查:(1)你是否被诊断患有自闭症谱系障碍?(2)你直系亲属中有多少人被诊断患有自闭症谱系障碍?结果显示,数学组有7例自闭症(占1.85%),而对照组有1例自闭症(占0.24%),相差9倍,具有显著性。在控制性别和总体抽样的情况下,这表明数学家患自闭症谱系障碍的几率增加了三到七倍。数学组的直系亲属中有1405人中有7例(占0.5%)自闭症,而对照组的直系亲属中有1669人中有2例(占0.1%)自闭症,这同样具有显著性差异。这些结果证实了自闭症与系统化之间的联系,并且鉴于自闭症与数学家的一级亲属之间的关联,表明这种联系是由基因决定的。