Vigani Aline Gonzalez
Departamento de Clínica Médica da Disciplina de Moléstias Infecciosas, Grupo de Estudo das Hepatites Virais, Universidade Estadual de Campinas (Unicamp), Campinas, Brazil.
Hospital de Clínicas, Universidade Estadual de Campinas, PO Box 6198, Campinas, São Paulo, 13083-970, Brazil.
Hepatol Int. 2013 Mar;7(1):16-27. doi: 10.1007/s12072-012-9356-5. Epub 2012 Mar 15.
Hepatitis C virus (HCV) infection and chronic renal diseases can be linked in two different ways. Some forms of renal disease are precipitated by HCV infection, while patients with end-stage renal disease are at increased risk for acquiring HCV infection. Patients with chronic HCV infection and renal disease have a poor prognosis. Most studies on treatment of HCV and renal diseases have been uncontrolled trials with small number of subjects. So, there is a lack of evidence-based recommendations and guidelines on the management of this condition. In this review, we will attempt to provide the most recent insights on HCV infection both as a extrahepatic manifestations and as a complication of end-stage renal patients.
丙型肝炎病毒（HCV）感染与慢性肾脏疾病可能通过两种不同方式相互关联。某些形式的肾脏疾病由HCV感染引发，而终末期肾病患者感染HCV的风险则会增加。慢性HCV感染合并肾脏疾病的患者预后较差。大多数关于HCV与肾脏疾病治疗的研究都是受试者数量较少的非对照试验。因此，在这种病症的管理方面缺乏循证推荐和指南。在本综述中，我们将试图就HCV感染作为一种肝外表现以及作为终末期肾病患者的一种并发症提供最新见解。
