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嗜酸性粒细胞终末器官表现谱

Spectrum of Eosinophilic End-Organ Manifestations.

作者信息

Akuthota Praveen, Weller Peter F

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA; Division of Allergy and Inflammation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.

Division of Allergy and Inflammation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.

出版信息

Immunol Allergy Clin North Am. 2015 Aug;35(3):403-11. doi: 10.1016/j.iac.2015.04.002. Epub 2015 Jun 17.

Abstract

Eosinophil-associated disorders can affect practically all tissues and organs in the body, either individually or in combination. This article provides an overview of end-organ manifestations of eosinophilia and discusses selected organ systems, including the upper and lower respiratory, cardiovascular, gastrointestinal, nervous, dermatologic, and renal systems. Mechanisms by which eosinophilia leads to end-organ damage are also considered.

摘要

嗜酸性粒细胞相关疾病几乎可影响身体的所有组织和器官,可单独影响,也可联合影响。本文概述了嗜酸性粒细胞增多的终末器官表现,并讨论了特定的器官系统,包括上、下呼吸道、心血管、胃肠道、神经、皮肤和肾脏系统。还探讨了嗜酸性粒细胞增多导致终末器官损伤的机制。

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